What is a line of therapy?
What is a line of therapy?
A line of therapy consists of ≥1 complete cycle of a single agent, a regimen consisting of a combination of several drugs, or a planned sequential therapy of various regimens (eg, 3-6 cycles of initial therapy with bortezomib-dexamethasone [VD] followed by stem cell transplantation [SCT], consolidation, and …
What is a first line therapy?
The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment.
What does 2nd line therapy mean?
Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren’t tolerated. It’s important to understand “lines of treatment” and how they differ from first line treatment and can play a role in clinical trials.
Why is line of therapy important?
Lines of therapy (LOT) and the number of prior lines of therapy influence the clinical benefit and even the magnitude of response to select regimens. 1 They are an important parameter to be determined in retrospective database studies evaluating oncology patients on various chemotherapy/immunotherapy regimens.
What is a line of chemo?
A PICC line is a long, thin, flexible tube known as a catheter. It is put into the arm to give chemotherapy and other medicines.
What is the first-line treatment for Covid 19?
The U.S. Food and Drug Administration (FDA) has approved remdesivir (Veklury) for the treatment of COVID-19 in certain situations. Clinical management of COVID-19 includes infection prevention and control measures and supportive care, including supplemental oxygen and mechanical ventilatory support when indicated.
What is the purpose of neoadjuvant therapy?
Neoadjuvant therapies are delivered before the main treatment, to help reduce the size of a tumor or kill cancer cells that have spread. Adjuvant therapies are delivered after the primary treatment, to destroy remaining cancer cells.
