What hormone controls spermatogenesis?
What hormone controls spermatogenesis?
The development and maintenance of spermatogenesis is dependent on the pituitary gonadotropins; FSH, and LH. Both hormones are secreted and regulated as a part of the HPG axis in response to the hypothalamic gonadotropin-releasing hormone (GnRH).
Which hormone regulates the process of spermatogenesis and sperm formation?
Testosterone
Testosterone is the major androgen in the testis that regulates spermatogenesis. Testosterone is produced by the Leydig cell in response to stimulation with luteinizing hormone (LH) and acts as a paracrine factor that diffuses into the seminiferous tubules.
Does LH stimulate spermatogenesis?
In men, LH stimulates testosterone production from the interstitial cells of the testes (Leydig cells). This androgen-binding protein causes high local concentrations of testosterone near the sperm, an essential factor in the development of normal spermatogenesis.
How do Gonadotropic hormones regulate spermatogenesis and testosterone production?
It targets Sertoli cells to stimulate the production of estrogens from androgens, and, together with testosterone, it induces the synthesis of androgen-binding proteins in these cells, which helps maintaining high levels of testosterone locally, necessary for spermatogenesis.
Which of the following hormones facilitate spermatogenesis and testosterone production?
FSH enters the testes, stimulating the Sertoli cells, which help to nourish the sperm cells that the testes produce, to begin facilitating spermatogenesis. LH also enters the testes, stimulating the interstitial cells, called Leydig cells, to make and release testosterone into the testes and the blood.
What triggers spermatogenesis?
FSH causes the Sertoli cells of the testes (which help nurse developing sperm cells) to begin the process of spermatogenesis in the testes. LH triggers the production of testosterone from the Leydig cells of the testis; testosterone causes the development of secondary sex characteristics in the male.
What hormones are important for male reproduction and how do they affect spermatogenesis?
Three hormones are the principle regulators of the male reproductive system: follicle-stimulating hormone (FSH) stimulates spermatogenesis; luteinizing hormone (LH) stimulates the production of testosterone; and testosterone stimulates the development of male secondary sex characteristics and spermatogenesis.
What is the function of Gonadotropic hormone?
A hormone made by a part of the brain called the hypothalamus. Gonadotropin-releasing hormone causes the pituitary gland in the brain to make and secrete the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In men, these hormones cause the testicles to make testosterone.
What is the function of spermatogenesis?
Purpose of Spermatogenesis The process of Spermatogenesis occurs to create mature male gametes, which then fertilize female gametes to create a zygote, a single-celled organism. This results in cell division and multiplication to create a fetus.
Which drugs inhibit spermatogenesis?
The FDA-approved drugs that have the potential to impair human spermatogenesis
| Generic name of drug | Adverse impact on human spermatogenesis |
|---|---|
| Nitrofurantoin | Spermatogenic arrest/decreased sperm count (high doses) |
| Dapsone | Orchitis, male infertility |
| Lamotrigine | Epididymitis (rare) |
| Clomipramine hydrochloride | Epididymitis (infrequent) |
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