How can you tell the difference between a fibroadenoma and a phyllodes tumor?
How can you tell the difference between a fibroadenoma and a phyllodes tumor?
Fibroadenomas grow up to 2-3 cm and then stop growing but phyllodes tumors grow continually and sometimes are to 40 cm big. Both these lesions have two components, epithelial and stromal. Clinically fibroadenomas are well circumscibed, hard, oval, movable lesions.
What is low grade phyllodes tumor?
AFIP defines low-grade phyllodes tumors as fibroepithelial neoplasms with well-defined borders, uniform leaf-like processes, rare to moderate mitoses (<3 mitoses per 10 high-power fields), mildly increased cellularity often with subepithelial accentuation, no to mild cytological atypia and no sarcomatous stromal …
Where do phyllodes tumors spread?
Outlook for Phyllodes Tumors Your outlook is excellent if you had a benign tumor removed with surgery. Treatment often cures malignant phyllodes tumors, but they’re more likely to grow back. They can spread beyond your breast to your lungs.
Are phyllodes tumors curable?
Treatment often cures malignant phyllodes tumors, but they’re more likely to grow back. They can spread beyond your breast to your lungs. Women with malignant phyllodes tumors still have a high survival rate.
Can Phyllodes spread?
Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).
What is the histology of fibroadenomas and phyllodes tumors?
It was concluded that fibroadenomas and phyllodes tumors arise from intralobular fibrous tissue, both changes have very close histology in the beginning and divergent growth starts later. Differences are present in stromal component. Phyllodes tumor has two component stroma.
What is a phyllodes tumor of the breast?
Phyllodes tumors and fibroadenomas are the most common benign breast tumors. They arise from intralobular fibrous tissue as a unique lesion and after a period of time they differentiate in two direction: to fibroadenoma and to phyllodes tumors.
What is the cytopathology of fibroadenoma?
Cytology description 1 Usual (adult type) fibroadenoma: biphasic population composed of abundant spindle stromal cells and naked nuclei,… 2 Myxoid fibroadenoma: high cellularity with stroma and epithelium embedded in myxoid background ( Diagn Cytopathol… More
Are phyllodes tumors on cytology discordant?
Among the 24 cases labeled as phyllodes tumor on cytology, 17 were benign phyllodes, 03 borderline phyllodes and 3 were malignant. All the three malignant phyllodes had been diagnosed as malignant on cytology. One benign phyllodes tumor was discordant on histopathology and was reported as a fibroadenoma. The two discordant cases were reviewed.
