What is ganglioside made up of?

What is ganglioside made up of?

Gangliosides are glycosphingolipids composed of a ceramide lipid tail attached through glycosidic linkage to a glycan headgroup containing one or more sialic acid residues (Figure 1).

What are the functions of ganglioside?

Gangliosides function as antigens or receptors by recognizing specific molecules (lectins), including bacterial toxins, at the cell surface and by modulating the charge density at the membrane surface (see the section on Gangliosides and Disease below).

Is ganglioside a lipid?

Glycerophospholipids, sphingolipids, and cholesterol are the lipid components of cell membranes. Among these, sphingolipids are minor components. They belong to the external layer of the membrane (Feizi 1985) with the hydrophilic headgroup protruding toward the extracellular environment.

What is GM1 and GM2?

GM1 gangliosidosis has both central nervous system and systemic findings; while, GM2 gangliosidosis is restricted primarily to the central nervous system. Both disorders have autosomal recessive modes of inheritance and a continuum of clinical presentations from a severe infantile form to a milder, chronic adult form.

Is ganglioside a phospholipid?

Gangliosides are a group of sialic acid glycosphingolipids found in the plasma membrane of cells (6). Phospholipids are found in all plant and animal cell membranes, usually in the form of glycerophospholipids—FAs esterified to a glycerol backbone (9).

Are gangliosides acidic?

Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types.

Why are gangliosides degraded?

Gangliosides are degraded by lysosomal exoglycosidases. Several human diseases are caused by defects of degradative enzymes, resulting in massive accumulation of certain glycolipids, including gangliosides in the lysosomal compartment and other organelles in the brain and visceral organs.

Does ganglioside contain sphingosine?

In higher animals, C18- and C20-sphingosine are the most abundant sphingoid bases of gangliosides.

What is a d882 transistor?

2SD882 is a general purpose transistor and it is a quite high performance device, according to its features this transistor is an ideal to use in wide variety of educational, commercial and hobbyists electronic projects. D882 can be used for wide variety of switching and amplification purposes.

What is the use of a d882 power supply?

D882 can be used for wide variety of switching and amplification purposes. It is packed with some of very interesting features, the max collector current is 3A which is enough to drive many relays, LEDs, Bulbs, motors, some part of an electronic circuit etc. the minimum collector saturation voltage is only 0.3V.

What does the suffix -C mean on d882npn?

D882NPN Type Elektronische Bauelemente Plastic Encapsulate Transistors RoHS Compliant ProductA suffix of “-C” specifies halogen & lead-freeTO-1263.20.28.00.22.00.24.140.1FeaturesO2.80.1 O3.20.111.00.21.40.11 2 3o MAXIMUM RATINGS* TA=25 C unless otherwise noted 1.270.1Symbol Parameter Value Units15.30.2VCBO Collector-Base Voltage

What are the applications of 2sd2sd882?

2SD882 can be used in variety of different application. For example It can be used in power supply circuits, voltage regulator circuits, battery charger circuits, driving motors, switching any load under 3A etc.