How harmful is THF?
How harmful is THF?
* Tetrahydrofuran can cause headache, nausea and dizziness. Very high exposure can cause unconsciousness and death. * Tetrahydrofuran may damage the liver and kidneys. * Tetrahydrofuran is a FLAMMABLE LIQUID and a DANGEROUS FIRE HAZARD.
What is tetrahydrofuran used for?
Tetrahydrofuran (THF) is commonly used as solvent, reaction medium, and starting material for various syntheses in the chemical industry, for example, for preparing adhesives, special paints, coatings, fibers, in the extraction of specific active substances, for recrystallization of certain compounds or as starting …
Which drug has tetrahydrofuran ring in its structure?
Chemical structure of annonacin, an acetogenin. Eribulin (brand name: Halaven), a commercial thf-containing anticancer drug.
Why is tetrahydrofuran a good solvent?
THF is also a popular solvent choice for small-scale laboratory experiments, mainly because it can dissolve a wide variety of organic compounds and has a relatively low boiling point. The low boiling point is convenient because it makes the solvent easy to remove from the chemical reaction by evaporation.
What is the NFPA Health rating for tetrahydrofuran?
2
TETRAHYDROFURAN†
| Physical Properties | ||
|---|---|---|
| Lower explosive limit (LEL) | 2% | 11.8% |
| NFPA health rating | 2 | 3 |
| NFPA reactivity rating | 1 | |
| Vapor hazard ratio (VHR) |
Is methylene chloride a probable human carcinogen?
Because methylene chloride has been shown to induce increased numbers of benign and malignant neoplasms in rats and mice, it meets the criteria provided in the OSHA Cancer Policy for classifying a substance as a potential occupational carcinogen; therefore, NIOSH recommends that methylene chloride be considered a …
Can I buy tetrahydrofuran?
You can buy Tetrahydrofuran online, locally near you at a distribution center (US only) or you can call 512-668-9918 to order your chemicals by phone. Get information on the chemical specifications, properties and structure of Tetrahydrofuran.
How do you handle tetrahydrofuran?
THF must be stored in an air-impermeable container and placed in a dark area to prevent further promotion of the peroxide-forming reaction. Suitable fire control devices (such as fire extinguishers) must be available at locations where flammable or combustible liquids are stored.
Does tetrahydrofuran react with sodium?
Sodium—cesium alloy was permitted to react with tetrahydrofuran as a model for the lithium electrode. The products of this reaction were treated with methyl bromide. The NMR of the final products gives evidence that cleaved tetrahydrofuran reacts with more tetrahydrofuran to form derivatives of itself.
What is the freezing point of tetrahydrofuran?
-163.1°F (-108.4°C)
Tetrahydrofuran/Melting point
What is the molecular weight of tetrahydrofuran?
72.11 g/mol
Tetrahydrofuran/Molar mass
