What is the difference between diabetic ketoacidosis and hyperosmolar hyperglycemic nonketotic coma?

What is the difference between diabetic ketoacidosis and hyperosmolar hyperglycemic nonketotic coma?

DKA is characterized by ketoacidosis and hyperglycemia, while HHS usually has more severe hyperglycemia but no ketoacidosis (table 1). Each represents an extreme in the spectrum of hyperglycemia. The precipitating factors, clinical features, evaluation, and diagnosis of DKA and HHS in adults will be reviewed here.

Which condition occurs in HHS but not in DKA?

Fever due to underlying infection is common, and signs of acidosis (Kussmaul respiration, acetone breath) are usually absent. Gastrointestinal manifestations (abdominal pain, vomiting) frequently reported in patients with DKA are not typically present in HHS.

Why is a diabetic patient having the following signs and symptoms polydipsia polyuria and Polyphagia?

In people with diabetes, polydipsia is caused by increased blood glucose levels. When blood glucose levels get high, your kidneys produce more urine in an effort to remove the extra glucose from your body. Meanwhile, because your body is losing fluids, your brain tells you to drink more in order to replace them.

When managing diabetic ketoacidosis which intervention is appropriate?

Fluid replacement is one of the most important initial therapeutic interventions in the management of DKA. Patients are usually dehydrated and correcting this deficit will result in significant metabolic improvement (Kitabchi et al, 2004).

Which is worse HHS or DKA?

Hyperosmolar hyperglycemic state (HHS) is one of two serious metabolic derangements that occur in patients with diabetes mellitus (DM). It is a life-threatening emergency that, although less common than its counterpart, diabetic ketoacidosis (DKA), has a much higher mortality rate, reaching up to 5-10%.

Why is hyperglycemia more in HHS than DKA?

In addition, DKA patients tend to be younger than HHS patients, and thereby have a higher glomerular filtration rate. Accordingly, DKA patients have a greater ability to excrete glucose in urine and can thereby limit the hyperglycemia.

What is Hyperglycemic Nonketotic coma?

Hyperosmolar Hyperglycemic Nonketotic Coma – StatPearls – NCBI Bookshelf Hyperosmolar hyperglycemic syndrome (HHS) is a clinical condition that arises from a complication of diabetes mellitus. This problem is most commonly seen in type 2 diabetes. Won Frerichs and Dreschfeld first described the disorder around 1880.

What are diabetic ketoacidosis and hyperglycemic hyperosmolar state (HHS)?

Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are acute metabolic complications of diabetes mellitus that can occur in patients with both type 1 and 2 diabetes mellitus.

What are the signs and symptoms of diabetic ketoacidosis (DKA)?

The common clinical presentation of DKA and HHS is due to hyperglycemia and include polyuria, polyphagia, polydipsia, weight loss, weakness, and physical signs of dehydration such as dry buccal mucosa, sunken eye balls, poor skin turgor, tachycardia, hypotension and shock in severe cases.

What is the difference between DKA and hhnk?

Key Differences 1 DKA stands for Diabetic ketoacidosis. 2 DKA is one of the most common effects for a person who has diabetes whereas HHNK is one of the most uncommon effects for a person who has diabetes. 3 DKA is considered less dangerous among the two, whereas HHNK is considered extremely dangerous.

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