Which is better for PCOS Clomid or letrozole?

Which is better for PCOS Clomid or letrozole?

The authors concluded that, overall, letrozole was a more effective means of treating infertility than clomiphene for women with polycystic ovary syndrome, with evidence of higher rates of ovulation and rates of major congenital anomalies that were not significantly different.

How effective is letrozole for PCOS?

It has been reported that letrozole can inhibit estrogen levels by at least 97% to 99%. The other studies also reported that letrozole is effective in clomiphene-resistant patients, and also resulted in ovulation of 62% cases, and pregnancy of 14.7%.

How effective is letrozole for unexplained infertility?

Rates of conception (defined as having a positive pregnancy test) were 47% in the gonadotropin group, 35% in the clomiphene group, and 28% in the letrozole group. There was no significant difference in the time to conception among the 3 groups.

Should I take letrozole for fertility?

Femara (generic name is letrozole) is an oral drug which can be an effective fertility treatment for women with ovulation problems, or for those with unexplained infertility. This medication is in a class of drug called aromatase inhibitors.

Can letrozole cause twins?

The risk of twins with letrozole is estimated to be approximately 3-5%, which appears to be lower than the risk of twins with clomiphene citrate (7-8%), but is still higher than the risk of twins in a spontaneous pregnancy (2-3%). Although triplets and higher-order pregnancies are rare, these may occur <1% of the time.

Is letrozole stronger than Clomid?

Low dose letrozole of 2.5 mg appeared to have the highest success per cycle compared with Clomid (20% vs. 13%), although further studies are needed to determine the best dose for an individual patient. Most clinics use 5 mg of letrozole daily.

Does letrozole improve egg quality?

What is Letrozole (Femara) Letrozole is an aromatase inhibitor (lowers estrogen production) that can be used to induce ovulation in patients with irregular ovulation patterns or those who suffer from anovulation. It can also help to increase egg production in women who ovulate normally but have unexplained infertility.

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