What is osteoconductive material?

What is osteoconductive material?

Osteoconductive materials are calcium phosphate ceramics such as hydroxyapatite, tricalcium phosphate and bicomposite of both materials, calcium sulfate and bioactive glass-ceramics. Artificial hydroxyapatite and tricalcium phosphate have been used as bone graft extenders.

What is osteoinductive material?

Osteoinductive materials include autografts, demineralised bone matrix (DBM) and specific bone morphogenetic proteins (BMPs) which naturally form bone within the skeleton as well as extraskeletally8,10,11 The ideal bone regeneration system will be fashioned from an osteoinductive replacement material that elicits an …

What is bone grafting material made of?

Alloplastic grafts may be made from hydroxyapatite, a naturally occurring mineral (main mineral component of bone), made from bioactive glass. Hydroxyapatite is a synthetic bone graft, which is the most used now due to its osteoconduction, hardness, and acceptability by bone.

Are ceramics Osteoinductive?

In summary, Ca-P ceramics can be endowed with osteoinductivity by optimizing the material characteristics, including phase composition, ionic environment, macro- and micro-pore structure, topographical feature, bone-like apatite and nanostructure.

Is xenograft an osteoinductive?

Allografts and xenografts have osteoinductive and osteoconductive characteristics but lack the osteogenic properties of autografts [9-11].

What are osteoconductive properties?

Osteoconduction is the ability of bone-forming cells in the grafting area to move across a scaffold and slowly replace it with new bone over time. Osteoconductive materials serve as a scaffold onto which bone cells (osteoblasts and osteoclasts) can attach, migrate, grow and/or divide.

What is allograft?

Listen to pronunciation. (A-loh-graft) The transplant of an organ, tissue, or cells from one individual to another individual of the same species who is not an identical twin.

What is an allograft bone?

Allograft is bone harvested by a tissue bank from a cadaver for use in medical procedures. It can be prepared in a number of different forms (such as chips) for use in a spine fusion.

Is calcium phosphate Osteoinductive?

Calcium phosphates have been reported to possess osteoconductive and osteoinductive characteristics, and they aid in the osteogenic differentiation of mesenchymal stem cells [9, 10].

Is xenograft an osteoconductive?

Is tricalcium phosphate osteoconductive?

β-Tricalcium phosphate showed the highest amount of mineralized area per total area and statistically significant compared with PL/PG, calcium phosphate cement, and untreated control groups. The PL/PG gel does not have osteoconductive properties and performed similar to empty control.

How does an osteoinductive graft induce bone growth?

Osteoinduction is the capability of the graft materials to induce formation of the bone-forming cells via differentiation of multipotent mesenchymal stem cells (MSCs) of the surrounding host tissues to produce osteoprogenitor cells followed by development of osteoblasts.