Why is metaphysis affected in osteomyelitis?

Why is metaphysis affected in osteomyelitis?

Hematogenous osteomyelitis is the most frequent type and primarily affects the metaphysis because the bacteria travel through vascular tunnels and adhere to the bone matrix. Animal models show that bone infection becomes more likely after trauma.

Why osteomyelitis is common in metaphysis in children?

Acute hematogenous osteomyelitis (AHO) is particularly common in children <5 years of age and typically affects the metaphysis because of the rich but slow blood flow of the growing bone.

Which site of long bone is more prone to osteomyelitis?

Among children and teens, the long bones of the legs and arms are most frequently affected. In adults, osteomyelitis most often affects the vertebrae of the spine and/or the hips.

Which is the most common cause of hematogenous osteomyelitis?

Acute hematogenous osteomyelitis usually occurs after an episode of bacteremia in which the organisms inoculate the bone. The organisms most commonly isolated in these cases include S aureus, Streptococcus pneumoniae, and Haemophilus influenza type b (less common since the use of vaccine for H influenza type b).

What is metaphysis of bone?

The metaphysis is the region where the epiphysis joins the diaphysis; in a growing bone this corresponds to the calcified layer of the epiphyseal plate together with the interdigitating bone (see Figure 4.19). The interface between the hypertrophic and calcified layers is sometimes referred to as the tidemark.

What is the epidemiology of osteomyelitis?

Incidence of osteomyelitis is approximately 13 per 100,000 in children and approximately 90 per 100,000 in adults. Hematogenous osteomyelitis occurs predominantly in children and elderly patients while osteomyelitis due to contiguous infection is most common in adults.

What is Sequestrum?

Definition of sequestrum : a fragment of dead bone detached from adjoining sound bone.

What is are common local signs of osteomyelitis?

Signs and symptoms of osteomyelitis include:

• Fever.
• Swelling, warmth and redness over the area of the infection.
• Pain in the area of the infection.
• Fatigue.

What happens in the metaphysis?

function in bone structure This region (metaphysis) functions to transfer loads from weight-bearing joint surfaces to the diaphysis. Finally, at the end of a long bone is a region known as an epiphysis, which exhibits a cancellous internal structure and comprises the bony substructure of the joint surface.

Is metaphysis and Physeal the same?

Long bones in children have four distinct segments (Figure 1): The epiphysis is the region of bone adjacent to the joint surface. Below it lies the physis, the area where growth occurs. Distal to that is the metaphysis, a flared region of bone, and below that lies the narrower shaft of the bone, or diaphysis.

What is sequestrum in osteomyelitis?

Sequestrum formation is a complication of chronic osteomyelitis. The bone infarction results from loss of the blood supply to a segment of bone, due to the inflammatory process. Bone infarction is prone to occur in this situation because the inflammatory exudate is confined within a rigid bony cavity.

Where does osteomyelitis occur?

Osteomyelitis is inflammation or swelling that occurs in the bone. It can result from an infection somewhere else in the body that has spread to the bone, or it can start in the bone — often as a result of an injury. Osteomyelitis is more common in younger children (five and under) but can happen at any age.