What is metastatic lobular carcinoma?
What is metastatic lobular carcinoma?
Invasive lobular carcinoma is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast. Invasive cancer means the cancer cells have broken out of the lobule where they began and have the potential to spread to the lymph nodes and other areas of the body.
Does lobular breast cancer respond well to chemotherapy?
Unfortunately, lobular breast cancers don’t always respond to chemotherapy as well as other breast cancers, and some forms are also less responsive to hormone therapy. For this reason, it is important that we find new and more effective treatments to give these patients the best chances of survival.
Why are lobular cancers sneaky?
Instead of clustering together, lobular cells spread out single file like tree branches or spider webs or mesh, which explains why surgeons and oncologists often refer to it as “sneaky” or “insidious.” Because the cells don’t stick together well, there’s often no lump, making it harder for women to find during self- …
What does the word lobular mean?
Definition of lobular : of, relating to, affecting, or resembling a lobule.
Does lobular breast cancer return?
The surgical treatment of patients with invasive lobular carcinoma is still controversial due to its different clinical and pathological features. Most studies report local recurrence after relatively short follow-up periods, which is usually 5 years.
What is the best treatment for lobular breast cancer?
ILC is treated with a lumpectomy or mastectomy, depending on the size and location of the tumor. In addition, your medical oncologist and radiation oncologist may recommend chemotherapy and/or radiation. Hormonal therapy is nearly always part of the treatment for lobular cancers.
What does a lobulated mass mean?
US image shows the mass (arrows), which was prospectively described as “lobulated,” a term that is not a BI-RADS US descriptor. The lesion has less than three undulations and therefore can be described as having an oval shape.
Where are the lobules in the breast?
There are many different parts to female breast anatomy, including: Lobes: Each breast has between 15 to 20 lobes or sections. These lobes surround the nipple like spokes on a wheel. Glandular tissue (lobules): These small sections of tissue found inside lobes have tiny bulblike glands at the end that produce milk.
What does lobular structure mean?
composed of, having the form of, or pertaining to lobules or small lobes.
Is lobular breast cancer worse than ductal?
An analysis of the largest recorded cohort of patients with invasive lobular breast cancer (ILC) demonstrates that outcomes are significantly worse when compared with invasive ductal breast cancer (IDC), highlighting a significant need for more research and clinical trials on patients with ILC.
Is lobular breast cancer hereditary?
Hereditary lobular breast cancer is a rare inherited cancer predisposition associated with pathogenic CDH1 (gene) germline mutations, and without apparent correlation with the hereditary diffuse gastric cancer syndrome.
Is lobular cancer worse than ductal cancer?
