What is mucoid conversion?
What is mucoid conversion?
This suggests that mucoid conversion is a response to oxygen radical exposure and that this response is a mechanism of defence by the bacteria. This is the first report to show that PMNs and their oxygen radicals can cause this phenotypic and genotypic change which is so typical of the intractable form of P.
What is mucoid Pseudomonas?
Mucoid Pseudomonas aeruginosa is an im- portant respiratory pathogen in patients with cystic fibro- sis, and once acquired is virtually impossible to eradicate.
Does Pseudomonas require growth factors?
PSEUDOMONAS | Pseudomonas aeruginosa The optimum growth temperature of P. aeruginosa is 37°C. Growth occurs at temperatures as high as 42°C, but not at 4°C. It does not require organic growth factors, and is able to multiply on a wide range of substrates (≥ 82 organic compounds).
What is mucoid phenotype?
The mucoid phenotype in P. aeruginosa is defined by overproduction of the polyanionic exopolysaccharide alginate (14). Nonmucoid, environmental isolates of P. aeruginosa initially colonize CF patients (15). However, exposure to host-derived mutagens (e.g., H2O2 and LL-37) promotes mutation of mucA (see Fig.
Is Pseudomonas a superbug?
Researchers have recently revealed the virulence regulatory mechanism in Pseudomonas aeruginosa, a superbug which is common in patients with a weak immune system and is resistant to many antibiotics. The findings pave ways for identifying good antibiotic targets for new drug development.
How do you grow Pseudomonas?
P. aeruginosa grows well on LB broth, but can also utilize a wide range of compounds as sole carbon and/or nitrogen sources. To study growth on these sole nutrient sources, various defined minimal media are used to grow P. aeruginosa such as MOPS (3-(N-Morpholino) Propane-Sulfonic Acid) medium, M9, or M63.
What is microbiology mucoid?
1 : resembling mucus. 2 : forming large moist sticky colonies —used of dissociated strains of bacteria. mucoid.
