What is the meaning of medoxomil?

What is the meaning of medoxomil?

mə-dŏksə-mĭl. A univalent organic group, C5 H5 O3 , chiefly used in combination with olmesartan as a prodrug. noun. A univalent organic group, C5 H5 O3 , chiefly used in combination with olmesartan as a prodrug.

Is olmesartan a prodrug?

Olmesartan medoxomil (OM) is a prodrug type angiotensin II type 1 receptor antagonist widely prescribed as an antihypertensive agent.

What kind of drug is olmesartan?

Olmesartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes the blood vessels to tighten. As a result, olmesartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.

Are olmesartan and olmesartan medoxomil the same?

Olmesartan medoxomil, a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract. Olmesartan is a selective AT1 subtype angiotensin II receptor antagonist.

What is olmesartan medoxomil used for?

Olmesartan is a medicine used to treat high blood pressure. Olmesartan helps prevent future strokes, heart attacks and kidney problems. This medicine is only available on prescription.

What is the half life of olmesartan medoxomil?

The terminal elimination half-life of olmesartan varied between 10 and 15 hours after multiple oral dosing. Steady state was reached after the first few doses and no further accumulation was evident after 14 days of repeated dosing. Renal clearance was approximately 0.5 – 0.7 L/h and was independent of dose.

Is olmesartan medoxomil an ACE inhibitor?

These findings suggest that olmesartan may exhibit an ACE inhibitory action in addition to an Ang II receptor blocking action, prevent an increase in Ang II level, and protect cardiovascular remodeling through an increase in cardiac nitric oxide production and endogenous Ang-(1-7) via over-expression of ACE2.

Is olmesartan medoxomil a blood thinner?

Olmesartan is a type of blood pressure-lowering medicine called an angiotensin receptor blocker. Like other angiotensin receptor blockers, olmesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.

Is medoxomil a diuretic?

Benicar HCT (olmesartan medoxomil-hydrochlorothiazide) is a combination of an angiotensin II receptor antagonist and a thiazide diuretic (water pill) used to treat high blood pressure (hypertension).

Which is better olmesartan or telmisartan?

Both telmisartan and olmesartan lower cholesterol levels, but compared to olmesartan, telmisartan is better at lowering LDL (“bad”) cholesterol levels.