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What is benzylpenicillin sodium used for?

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What is benzylpenicillin sodium used for?

Benzylpenicillin is indicated for most wound infections, pyogenic infections of the skin, soft tissue infections and infections of the nose, throat, nasal sinuses, respiratory tract and middle ear, etc.

Is benzyl penicillin a natural penicillin?

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption.

What are the side effects of benzyl penicillin?

What are the side effects of Penicillin G Benzathine (Bicillin L-A)?

  • pain, numbness, tingling, burning, or feeling cold;
  • pale or mottled skin, blue-colored lips, fingers, or toes;
  • severe pain, tingling, weakness, or swelling in your lower leg;
  • weakness in your arms or legs; or.

Why is benzylpenicillin prescribed for frequent doses?

Benzylpenicillin (t½ 0.5 h) (penicillin G) has to be given with spaced doses that have to be large to maintain a therapeutic concentration, but the large therapeutic ratio of penicillin allows the resulting fluctuations to be tolerable.

What disease is treated with penicillin?

Penicillin G sodium is a fast-acting antibiotic that fights bacteria in your body. Penicillin G sodium is used to treat many different types of severe infections, including strep infections, meningitis, anthrax, pneumonia, gonorrhea, and syphilis.

How is penicillin excreted?

All of the penicillins are readily and actively secreted by the renal tubles and most are eliminated, almost completely unchanged, in the urine. The majority are excreted in small quantities in the bile, but this is a major route for elimination of nafcillin from the body.

What is the target for clavulanic acid?

Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects.

What is one of the most common adverse effects of benzylpenicillin?

COMMON side effects

  • headache.
  • nausea.
  • diarrhea.

Can benzylpenicillin treat syphilis?

A single intramuscular injection of long acting Benzathine penicillin G (2.4 million units administered intramuscularly) will cure a person who has primary, secondary or early latent syphilis.

What bacteria is sensitive to penicillin?

The natural penicillins have activity against non-beta-lactamase producing gram-positive cocci, including viridans streptococci, group A streptococci, Streptococcus pneumoniae, and anaerobic streptococcus (Peptostreptococcus, Peptococcus sp.). Enterococcus sp. is most susceptible to the natural penicillins.

How are antibiotics excreted from the body?

Both unchanged antibiotics and antibiotic metabolites are removed from the body by excretion pathways. Excretion from the kidneys (as urine) is a major route of drug elimination; excretion into the bile (as feces) from the liver is another.

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