What type of vaccine is ACAM2000?

What type of vaccine is ACAM2000?

ACAM2000 (Smallpox (Vaccinia) Vaccine, Live) is a smallpox vaccine manufactured by Sanofi Pasteur Biologics Co. of Cambridge Massachusetts. The medication provides for immunization against smallpox disease for people determined to be at high risk for smallpox infection.

What was the name of the smallpox vaccine?

FDA licensed Smallpox (Vaccinia) Vaccine, Live, with the proprietary name ACAM2000, for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection.

Who invented ACAM2000?

ACAM2000, developed by Acambis and manufactured by Sanofi Pasteur, is a second-generation lyophilized preparation of purified virus (grown in Vero cell line) in HEPES (hydroxyethylpiperazine ethanesulfonic acid)-buffered saline, pH 7.4, containing 1% to 4% human serum albumin USP, 5% mannitol, and trace amounts of …

Can you still get smallpox if vaccinated?

Is it possible for people to get smallpox from the vaccination? No. The smallpox vaccine does not contain smallpox virus and cannot spread or cause smallpox. However, the vaccine does contain another virus called vaccinia which is live in the vaccine.

Does smallpox vaccine still exist?

The smallpox vaccine is no longer available to the public. In 1972, routine smallpox vaccination in the United States ended. In 1980, the World Health Organization (WHO) declared smallpox was eliminated. Because of this, the public doesn’t need protection from the disease.

What are the risks of the ACAM2000 ® vaccine?

The risk for experiencing serious vaccination complications must be weighed against the risks for experiencing a potentially fatal smallpox infection. ACAM2000 ® is indicated for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection.

What does acacam2000 stand for?

ACAM2000 (Smallpox (Vaccinia) Vaccine, Live) is a smallpox vaccine manufactured by Emergent BioSolutions, an American specialty biopharmaceutical company.

Can the ACAM2000 vaccine cause myocarditis and/or pericarditis?

Suspected cases of myocarditis and/or pericarditis have been observed in healthy adult primary vaccinees (at an approximate rate of 5.7 per 1000, 95% CI: 1.9-13.3) receiving ACAM2000 [see Warnings and Precautions (5.1)].

How is acacam2000 reconstituted for lyophilization?

ACAM2000 is reconstituted by addition of 0.3 mL of diluent to the vial containing lyophilized vaccine. Note: this 0.3 mL of diluent is not the entire content of the diluent vial.

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