What class of drug is Urapidil?

What class of drug is Urapidil?

Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist.

Is Urapidil available in the us?

Urapidil (not available on the US market) is an alpha1 receptor antagonist that has both a peripheral effect and a central effect.

How does Urapidil work?

Urapidil works mainly by antagonizing postsynaptic alpha-1-adrenergic receptors and stimulating 5-HT1A receptors, a double mechanism that provides vasodilation with moderate decrease in blood pressure without reflex tachycardia. Adverse side effects are rare and clinically unimportant.

What is Indoramin used for?

Indoramin is used to treat a condition where your prostate becomes bigger, called ‘benign prostatic hyperplasia’ or BPH. The prostate is a gland found underneath the bladder in men.

How does phentolamine work?

Phentolamine given by injection causes blood vessels to expand, thereby increasing blood flow. When injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.

What is the mechanism of action of Fenoldopam?

Fenoldopam has a unique mechanism of action compared to other antihypertensive medications: it is a dopamine (D1) receptor agonist that results in decreased peripheral vascular resistance primarily in renal capillary beds, thus promoting increased renal blood flow, natriuresis, and diuresis.

Is Indoramin an alpha blocker?

Indoramin belongs to a group of medicines known as alpha-blockers. It works by blocking the action of certain nerve impulses.

What type of drug is Phenoxybenzamine?

Phenoxybenzamine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension) due to a disease called pheochromocytoma.

What is another name for phentolamine?

Phentolamine, sold under the brand name Regitine among others, is a reversible nonselective α-adrenergic antagonist.

What are the side effects of clonidine?

Side Effects

• Anxiety.
• blistering, burning, crusting, dryness, or flaking of the skin.
• chest pain or discomfort.
• confusion as to time, place, or person.
• decreased urine output.
• dilated neck veins.
• fast, pounding, or irregular heartbeat or pulse.
• general feeling of discomfort or illness.

What do alpha-1 blockers do?

The alpha-1 adrenergic receptor antagonists (also called alpha-blockers) are a family of agents that bind to and inhibit type 1 alpha-adrenergic receptors and thus inhibit smooth muscle contraction. Their major uses are for hypertension and for symptomatic benign prostatic hypertrophy.