What drugs are contraindicated in pheochromocytoma?
What drugs are contraindicated in pheochromocytoma?
Drugs that increase sympathetic tone such as ketamine, ephedrine, pancuronium, metoclopramide should not be used in patients with pheochromocytoma [22]. Histamine provoking drugs such as morphine and atracurium should also be avoided.
Which of the following drug is used for diagnosis of pheochromocytoma?
Drugs used for Pheochromocytoma Diagnosis
| Drug name | Rating | Rx/OTC |
|---|---|---|
| View information about phentolamine phentolamine | Rate | Rx |
| Generic name: phentolamine systemic Drug class: miscellaneous cardiovascular agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
How much does Demser cost?
The cost for Demser oral capsule 250 mg is around $40,787 for a supply of 100 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Which is the most common surgical treatment option for a person with pheochromocytoma?
Surgical resection of the tumor is the treatment of choice for pheochromocytoma and usually results in cure of the hypertension.
Why alpha blockers are used in treatment of pheochromocytoma?
Pheochromocytoma is a rare, catecholamine (ex. adrenaline) secreting tumor that requires preoperative alpha blockade to minimize intraoperative hemodynamic instability, thereby reducing intra- and postoperative morbidity and mortality.
What is Demser used for?
This medication is used to treat high blood pressure in people with a certain adrenal gland tumor (pheochromocytoma). Metyrosine is used to prevent high blood pressure before and immediately after surgery to remove the tumor. It is also used long-term in people who cannot have the surgery.
What if a patient with pheochromocytoma is given a beta blocker before alpha blocker?
Beta-blockers must never be started prior to adequate alpha-blockade, since in the absence of beta-2-mediated vasodilation, profound unopposed alpha-mediated vasoconstriction may lead to hypertensive crisis or pulmonary edema.
Can pheochromocytoma go away?
Pheochromocytoma is rare, and it is not usually cancerous. However, without treatment, it can lead to serious complications. Removing the tumor will usually cause the symptoms to go away. However, a doctor may recommend lifelong follow up, as some pheochromocytomas can recur.
Is demser (Metyrosine) effective in the treatment of pheochromocytoma?
While the preoperative use of DEMSER (metyrosine) in patients with pheochromocytoma is thought to decrease intraoperative problems with blood pressure control, DEMSER (metyrosine) does not eliminate the danger of hypertensive crises or arrhythmias during manipulation of the tumor, and the alpha-adrenergic blocking drug, phentolamine, may be needed.
What are the treatment options for a pheochromocytoma?
The primary treatment for a pheochromocytoma is surgery to remove the tumor. Before you undergo surgery, your doctor will prescribe specific blood pressure medications that block the actions of the high-adrenaline hormones to lower the risk of developing dangerously high blood pressure during surgery.
What is demdemser used to treat?
DEMSER (metyrosine) is indicated in the treatment of patients with pheochromocytoma for: Preoperative preparation of patients for surgery. Management of patients when surgery is contraindicated. Chronic treatment of patients with malignant pheochromocytoma.
How can I prevent low blood pressure after pheochromocytoma surgery?
A high-salt diet will draw more fluid inside the blood vessels, preventing the development of low blood pressure during and after surgery. In most cases, your surgeon removes the entire adrenal gland with a pheochromocytoma with minimally invasive surgery.
