What is the most common presenting symptom of MS?
What is the most common presenting symptom of MS?
Fatigue. Fatigue is one of the most common symptom of MS, reported by at least 75% of patients with the disease.
How do you trigger multiple sclerosis?
Multiple sclerosis (MS) triggers include anything that worsens your symptoms or causes a relapse….Here are some of the most common triggers you may experience with MS and tips to avoid them.
- Stress.
- Heat.
- Childbirth.
- Getting sick.
- Certain vaccines.
- Vitamin D deficiency.
- Lack of sleep.
- Poor diet.
What is the mechanism of action of the treatment for MS?
Immunomodulators (interferon-beta and glatiramer acetate), which shift the immune balance toward an anti-inflammatory response, are at the frontline of treatments for MS. Immunomodulators have targeted actions on the immune system, but affect a greater number of immunopathogenic processes than monoclonal antibodies.
What does MS do to myelin?
Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. In this disorder, your immune system attacks the myelin sheath or the cells that produce and maintain it. This causes inflammation and injury to the sheath and ultimately to the nerve fibers that it surrounds.
How do multiple sclerosis medications work?
These medicines slow down the advance of your disease and prevent flare-ups. The drugs work by curbing the immune system — your body’s main defense against germs — so that it doesn’t attack the protective coating called myelin that surrounds the nerves. Some drugs come as injections under your skin or into a muscle.
What are some symptoms associated with multiple sclerosis that might explain the importance of the myelin sheath?
In multiple sclerosis, the protective coating on nerve fibers (myelin) in the central nervous system is damaged. This creates a lesion that, depending on the location in the central nervous system, may cause symptoms such as numbness, pain or tingling in parts of the body.
How is convulsive status epilepticus (CSE) diagnosed?
The diagnosis of convulsive status epilepticus is made clinically but requires emergent neuroimaging and laboratory studies to identify a potential etiology. A head computed tomography (CT) scan is appropriate in most situations and most easily obtained.
What is the pathophysiology of multiple sclerosis (MS)?
See Treatment and Medication for more detail. Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system (CNS), destroying the myelin and the axon in variable degrees.
What are the medical conditions that may be confused with convulsions?
Medical Conditions That May Be Confused With a Convulsion. Seizure/epilepsy –Some seizures, specifically tonic clonic seizures, manifest as convulsions, while other seizure types do not resemble convulsions. Similarly, some convulsions are seizures, while some are not.
What are considerations in service connection for neurological and convulsive disorders?
This topic contains general information about neurological and convulsive disorders, including considerations in service connection (SC) for neurological disorders identifying epilepsy evaluating progressive spinal muscular atrophy other organic diseases of the nervous system under 38 CFR 3.309(a), and evaluating vertigo.