What is nitnitrazepam and how does it work?
What is nitnitrazepam and how does it work?
Nitrazepam works by affecting the way certain brain chemicals (neurotransmitters) transmit messages. This has a calming effect which helps you to sleep. It works well in the short term, with one week’s treatment normally being sufficient, although up to three weeks of treatment are sometimes required.
What is the generic name for nitrazepam?
Generic Names 1 Nitrazepam (OS: USAN, JAN, DCIT, BAN) 2 Nitrazépam (OS: DCF) 3 LA 1 (IS) 4 Ro 45360 (IS) 5 Ro 53059 (Roche) (IS) 6 Nitrazepam (PH: BP 2018, JP XVII, Ph. Eur. 9, Ph. Int. 6) 7 Nitrazépam (PH: Ph. Eur. 9) 8 Nitrazepamum (PH: Ph. Eur. 9, Ph. Int. 6)
Does discontinuation of nitrazepam cause rebound insomnia?
Discontinuation of nitrazepam produced rebound insomnia after short-term single nightly dose therapy. Benzodiazepines require special precautions if used in alcohol- or drug-dependent individuals and individuals with comorbid psychiatric disorders.
Is it safe to take nitrazepam for recreational use?
Recreational use of nitrazepam is common. A monograph for the drug says: “Treatment with nitrazepam should usually not exceed seven to ten consecutive days. Use for more than two to three consecutive weeks requires complete re-evaluation of the patient.
Is nitnitrazepam lipophilic or lipidophilic?
Nitrazepam is a nitrobenzodiazepine. It is a 1,4 benzodiazepine, with the chemical name 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4- benzodiazepin-2-one . It is long acting, lipophilic, and metabolised hepatically by oxidative pathways.
Is nitrazepam safe for intractable epilepsy?
Nitrazepam therapy, compared with other drug therapies, increases risk of death when used for intractable epilepsy in an analysis of 302 patients. The risk of death from nitrazepam therapy may be greater in younger patients (children below 3.4 years in the study) with intractable epilepsy.
How much Nitrazepam is safe to take for insomnia?
The recommended adult dose of nitrazepam when taken for insomnia is 5 mg to 10 mg taken at bedtime. Seniors may be more likely to experience unwanted effects of this medication and should start with 2.5 mg taken at bedtime. The lowest effective dose should be used.
