Can granular casts be normal?
Can granular casts be normal?
Casts in urine from normal individuals are few or none (and are usually hyaline or granular in nature).
Why do granular casts form?
Granular casts are generally the result of degeneration of cells in cellular casts [I3]. Their significance lies with the cast from which they were formed. Granular casts may also be the result of direct ag- gregation of serum proteins and other sub- stances into a matrix of Tamm-Horsfall mucoprotein.
What does a granular cast look like?
Granular casts Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise.
Is it normal to have cast in urine?
Normally, the presence of casts in the urine is considered to be an unusual finding. However, small amounts of hyaline casts (between 0–2 casts per low power field of the microscope) may be detected in the urine of healthy individuals without necessarily indicating a serious condition like kidney disease.
What causes granular cast in urine?
Granular casts are a sign of many types of kidney diseases. Red blood cell casts mean there is a microscopic amount of bleeding from the kidney. They are seen in many kidney diseases. Renal tubular epithelial cell casts reflect damage to tubule cells in the kidney.
Why is granular cast in urine?
What is the normal range of WBC in urine?
A normal range in the bloodstream is between 4,500-11,000 WBCs per microliter. A normal range in the urine is lower than in the blood, and may be from 0-5 WBCs per high power field (wbc/hpf).
What does granular cast in urine mean?
Granular casts are a sign of many types of kidney diseases. Red blood cell casts mean there is a microscopic amount of bleeding from the kidney. They are seen in many kidney diseases. Renal tubular epithelial cell casts reflect damage to tubule cells in the kidney.
What does granular cast in urine sample indicate?
There are different interpretations of having a cast in the urine. It all depends on the type of cast. If it is a granular cast, it could indicate underlying kidney disease. If it is a red blood cell cast, it could be a sign of bleeding from the kidneys, which could be associated with different types of kidney-related diseases.
What are abnormal casts in the urine?
Abnormal results may include: Fatty casts are seen in people who have lipids in urine, usually as a complication of nephrotic syndrome. Granular casts are a sign of underlying kidney disease. Hyaline casts are usually caused by dehydration, exercise, or diuretic medicines. Red blood cell casts are a sign of bleeding into the kidney tubule.
What causes fatty casts in urine?
Fatty casts: These casts in urine occur due to disintegration of lipid-rich epithelial cells which are nothing but yellowish tanned hyaline casts with attachments of fat globules. Fatty casts typically affect patients with urinary lipids, which in turn is often a complication of nephrotic syndrome.
