Can I get pregnant on triptorelin?

Can I get pregnant on triptorelin?

No, triptorelin is not a birth control medicine. You can still get pregnant even if your periods have stopped. Hormone changes that happen when taking triptorelin increase the risk of losing your baby if you get pregnant (miscarriage).

Does triptorelin cause fatigue?

Do not take Decapeptyl SR 11.25 mg if you are pregnant or breast-feeding. Driving and using machines: You may feel dizzy, tired or have problems with your sight such as blurred vision. These are possible side effects of treatment or from the underlying disease.

How does GnRH help endometriosis?

How they work. All the GnRH agonists work in exactly the same way. When used continuously for periods of longer than 2 weeks, they stop the production of oestrogen by a series of mechanisms. This deprives the endometrial implants of oestrogen, causing them to become inactive and degenerate.

Does GnRH stop menstruation?

Oestrogen levels will start to increase once the last GnRH analogue injection has worn off. The return of ovulation and menstrual periods should normally return within 6 – 10 weeks, the longer the course of treatment the longer it may take for periods to return.

How long does it take triptorelin to work?

Triptorelin can increase certain hormones when you first start using this medicine or after each new injection. This may cause symptoms of prostate cancer or precocious puberty to get worse for a short time. These side effects should get better within 1 to 2 months.

Is tibolone a hormone?

Instead of actual hormones (such as oestrogen and progestogen) it contains tibolone. Your body breaks down tibolone to make hormones. Its effects and benefits are similar to combined HRT.

What are the side effects of triptorelin?

Triptorelin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache.
• heartburn.
• constipation.
• hot flashes (a sudden wave of mild or intense body heat), sweating, or clamminess.
• decreased sexual ability or desire.

What are the side effects of gonadotropin releasing hormone GnRH agonists?

Common side effects of the GnRH agonists and antagonists include symptoms of hypogonadism such as hot flashes, gynecomastia, fatigue, weight gain, fluid retention, erectile dysfunction and decreased libido. Long term therapy can result in metabolic abnormalities, weight gain, worsening of diabetes and osteoporosis.

Can you get pregnant after GnRH?

Results: The total pregnancy rate of 78% (47/60) in GnRH-a treatment group is significantly higher than 55% (23/42) in non-GnRH-a treatment group (P=0.012). There is no significant difference in spontaneous abortion rate between the GnRH-a treatment group and non GnRH-a treatment group (19% vs. 13%, P=0.465).

What are the side effects of gonadotropin releasing hormone agonist?

Is triptorelin a chemo?

RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as triptorelin, may protect normal ovarian cells from the side effects of chemotherapy.

Why is tibolone banned in US?

US regulators have rejected Organon’s enzyme replacement therapy Livial (tibolone) for the treatment of menopausal symptoms in women, prompting the company – the human healthcare unit of Dutch concern Akzo Nobel – to withdraw its application in the country.

Can Triptorelin be used to treat endometriosis?

When used off-label to treat endometriosis, hormonal add-back therapy (such as estrogens or progestins) is recommended at the start of treatment to reduce bone mineral loss. Use of triptorelin is generally limited to less than 6 or 12 months due to side effects.

What are the possible adverse effects of triptorelin?

Applies to triptorelin: intramuscular powder for injection, intramuscular powder for injection extended release. The most common adverse events were hot flushes, impotence, decreased libido, skeletal pain, and headache.

Does triptorelin need to be refrigerated?

The Trelstar and Triptodur brands of triptorelin are kept at room temperature before reconstitution (20°C to 25°C [68°F to 77°F]) and should be administered immediately after reconstitution. The Decapeptyl brand should be refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze and protect from light.

What is the mechanism of action of targettriptorelin?

Triptorelin causes an initial, transient, surge in FSH, LH, testosterone, and estradiol, which through a negative feedback loop is followed by a sustained decrease in FSH and LH and a significant reduction in ovarian and testicular steroidogenesis usually 2 to 4 weeks after initiation.