Can mifepristone be used alone?
Can mifepristone be used alone?
Misoprostol and mifepristone have been shown to be effective for medical abortion up to 9 weeks of gestation. When used alone, the successful complete abortion rate dropped to ~60%. It has been demonstrated that by adding water to misoprostol, the success rate rose to 92%.
Can I take misoprostol 12 hours after mifepristone?
Conclusions Our results suggest that vaginal misoprostol, 800 µg, can be used from 1 to 3 days after mifepristone, 200 mg, for early medical abortion, and need not be administered strictly 48 hours after mifepristone.
How long does mifepristone take to absorb?
Following oral administration of a single dose of 600 mg, mifepristone is rapidly absorbed, with a peak plasma concentration of 1.98 mg/l occurring approximately 90 minutes after ingestion.
Can I take misoprostol 20 hours after mifepristone?
The misoprostol should still be used if she didn’t already cramp and bleed and expel the pregnancy (mifepristone alone works about 65% of the time), but there is no need to repeat the dose of mifepristone. Research most strongly supports using misoprostol between 24-48 hours after the Mifepristone.
Can bleeding start after taking mifepristone?
Vaginal bleeding — similar to a menstrual period — will usually start 1 to 2 days after taking mifepristone, although some women may start bleeding earlier than this. In most cases, bleeding at this stage can be managed with regular sanitary pads.
What should you not do after taking mifepristone?
Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. Do not take other medicines unless they have been discussed with your doctor.
How many misoprostol should I take after mifepristone?
Vaginal misoprostol, 800 µg, can be used between 1 and 3 days after mifepristone, 200 mg, for abortion at up to 56 days’ gestation, increasing the flexibility of the regimen.
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