Does Bactrim cause thrombocytopenia?

Does Bactrim cause thrombocytopenia?

Chronic: Use of BACTRIM at high doses and/or for extended periods of time may cause bone marrow depression manifested as thrombocytopenia, leukopenia and/or megaloblastic anemia.

Which drug would be the most common cause of drug induced thrombocytopenia?

Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia. If a medicine prevents your bone marrow from making enough platelets, the condition is called drug-induced nonimmune thrombocytopenia.

Which antibiotics can cause low platelets?

Some prescribed medications can also cause thrombocytopenia, including:

• amiodarone.
• ampicillin and other antibiotics.
• cimetidine.
• piperacillin.
• seizure medications, such as carbamazepine.
• sulfonamides, such as trimethoprim-sulfamethoxazole.
• vancomycin.

Does drug induced thrombocytopenia go away?

The expected course is that recovery of thrombocytopenia begins within 1 to 2 days after the drug is discontinued and recovery is usually complete within a week. Platelet transfusions may be necessary to control overt hemorrhage; corticosteroids are commonly used because the diagnosis of ITP cannot be excluded.

Can antibiotics cause thrombocytopenia?

Antibiotic-induced immune thrombocytopenia (AIT) is a rare postoperative complication that can develop after the use of commonly used antibiotics in total joint arthroplasty.

Can zosyn cause thrombocytopenia?

Highlights. The first case of piperacillin-induced thrombocytopenia is reported in a dual heart and kidney transplant patient taking Zosyn. Four previous studies report patients with Zosyn -induced thrombocytopenia per history.

Does Rocephin cause thrombocytopenia?

Ceftriaxone causes drug-induced immune thrombocytopenia and hemolytic anemia: characterization of targets on platelets and red blood cells. Transfusion.

How do you rule out drug induced thrombocytopenia?

Five clinical criteria can help to establish the diagnosis of DITP6,10 : (1) exposure to the candidate drug was preceded thrombocytopenia; (2) recovery from thrombocytopenia was complete and sustained after discontinuing the candidate drug; (3) the candidate drug was the only drug used before the onset of …

Do antibiotics lower platelets?

Medications. Certain medications can reduce the number of platelets in your blood. Sometimes a drug confuses the immune system and causes it to destroy platelets. Examples include heparin, quinine, sulfa-containing antibiotics and anticonvulsants.

Does Cipro lower platelets?

Immediately after the administration of two doses of ciprofloxacin (400 mg twice daily), the platelet counts decreased to 6000/μL.

Can ofloxacin cause thrombocytopenia?

Although Fluoroquinolones are known to cause thrombocytopenia, Ofloxacin induced thrombocytopenia cases are reported rarely.