How common is SCA3?
How common is SCA3?
Worldwide, SCA3 is thought to be the most common spinocerebellar ataxia (SCA), comprising 20%-50% of families (reviewed in Klockgether et al [2019]).
What causes SCA1?
Mutations in the ATXN1 gene cause SCA1. The ATXN1 gene provides instructions for making a protein called ataxin-1. This protein is found throughout the body, but its function is unknown. Within cells, ataxin-1 is located in the nucleus .
What is SCA17?
Spinocerebellar ataxia type 17 (SCA17) is a rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by a variable clinical picture which can include dementia , psychiatric disorders, parkinsonism, dystonia , chorea, spasticity , and epilepsy .
How old is Erika from 1 litre of Tears?
Erika Sawajiri (沢尻 エリカ, Sawajiri Erika, born April 8, 1986) is a Japanese actress, singer, and model, who appeared in the fiction Japanese television drama 1 Litre of Tears, playing the role of a girl who suffered from the intractable disease spinocerebellar degeneration (SCD).
What is Erika Sawajiri famous for?
Erika Sawajiri (沢尻 エリカ, Sawajiri Erika, born April 8, 1986) is a former Japanese actress, singer, and model. After starting out as a junior model, Sawajiri transitioned to acting in 2002 and has starred in Break Through!, Shinobi: Heart Under Blade, and 1 Litre of Tears, for all of which she received several newcomer acting awards.
Why did Erika Sawajiri get arrested?
On November 16, 2019, she was arrested for drug possession, and during her trial in January 2020, she stated that she had no plans on continuing her career. Erika Sawajiri was born in Nerima, Tokyo to a Japanese father and an Algerian (Kabyle, raised in France) mother and is the youngest of three children.
How many copies did one litre of Tears sell in Japan?
The diary is later entitled, One Litre of Tears, which has sold over 1.1 million copies in Japan. Fifteen-year-old Ikeuchi Aya is an ordinary girl, soon to be high school student and daughter of a family who works at a tofu shop. As time passes, unusual things start happening to Aya.
https://www.youtube.com/watch?v=NcUdoTvE08g
