How do CNS stimulants treat narcolepsy?

How do CNS stimulants treat narcolepsy?

Stimulants increase wakefulness, vigilance, and performance. They are thought to alter midbrain dopaminergic activity, but the precise mechanism of action is unknown. Interpatient variability in the dosage required to alleviate excessive daytime sleepiness (EDS) is considerable and unpredictable.

What drugs cause hypersomnia?

Alcohol, marijuana and opiates are substances that can cause hypersomnia. These substances can also initiate other sleep issues that can result in daytime sleepiness. The prolonged use or withdrawal of substances can also cause hypersomnia and negatively impact sleep pattern and quality.

Is Xyrem approved for idiopathic hypersomnia?

With generic competition on the horizon for its older sleep disorder drug Xyrem, Jazz Pharmaceuticals plc gained an added indication for its GABA B receptor agonist Xywav as the FDA approved it for idiopathic hypersomnia (IH).

Is Wellbutrin used for narcolepsy?

Bupropion is a dopamine reuptake inhibitor that may be useful for the treatment of EDS associated with narcolepsy (100 mg three times daily). It may be especially useful in cases associated with atypical depression.

Are narcolepsy and hypersomnia the same?

Hypersomnia and narcolepsy are related but distinct medical terms. Narcolepsy is a specific neurological disorder that causes sudden attacks of deep sleep, while hypersomnia is a symptom, and refers to excessive daytime sleepiness more generally. Hypersomnia, or hypersomnolence, is a symptom of narcolepsy.

What drugs can cause narcolepsy?

Drug Abuse as a Cause of Narcolepsy

• Steroids, including prednisone.
• Diet pills.
• Drugs that treat high blood pressure, like beta blockers.
• Hormones, such as oral contraceptives.
• Attention deficit hyperactivity disorder stimulant medications.
• Some antidepressants.

What medicine is prescribed for excessive daytime sleepiness?

The clinical efficacy of modafinil, combined with its improved safety over CNS stimulants, has made it the most prescribed medication for the treatment of excessive sleepiness associated with narcolepsy.

Is idiopathic hypersomnia rare?

IH is quite rare, with only 1 or 2 people with IH for every 10,000. The cause is not well understood, but it is probably related to chemical imbalances in the parts of the brain that regulate sleep and wakefulness.

Are stimulants legally prescribed for narcolepsy?

Many patients in the narcolepsy community are lawfully prescribed CNS stimulants to manage excessive daytime sleepiness from narcolepsy. [If you take CNS stimulants.] I am a patient who is lawfully prescribed CNS stimulants to manage excessive daytime sleepiness from narcolepsy.

What is the Narcolepsy Network?

Narcolepsy Network is dedicated to supporting, connecting, and advocating for people with narcolepsy around the world. Approximately 1 out of every 2,000 people has narcolepsy, and it is estimated that only a quarter of those patients are ever diagnosed.

What is the rate of incidence for narcolepsy?

Approximately 1 out of every 2,000 people has narcolepsy, and it is estimated that only a quarter of those patients are ever diagnosed. The primary symptom of narcolepsy is excessive daytime sleepiness, and approximately 70% of people with narcolepsy also experience cataplexy (a sudden loss of muscle tone).

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