How do I switch from donepezil to rivastigmine patch?

How do I switch from donepezil to rivastigmine patch?

Switching cholinesterase inhibitors from oral donepezil to the rivastigmine patch, either immediately or following a 7-day washout period, is easy to accomplish and well tolerated and should therefore be considered in patients experiencing problems with efficacy and tolerability of oral donepezil.

Does Exelon come in pill form?

Exelon Capsules EXELON (rivastigmine tartrate) Capsules equivalent to 1.5 mg, 3 mg, 4.5 mg, or 6 mg of rivastigmine base are available as follows: 1.5 mg capsule – yellow, “Exelon 1,5 mg” is printed in red on the body of the capsule.

Is rivastigmine the same as Exelon?

Rivastigmine is a reversible cholinesterase inhibitor used to treat mild to moderate dementia caused by Alzheimer’s or Parkinson’s disease. Rivastigmine is available under the following different brand names: Exelon, and Exelon Patch.

How big is the Exelon patch?

Each 5 cm2 patch contains 9 mg rivastigmine base, with in vivo release rate of 4.6 mg/24 hours. Each 10 cm2 patch contains 18 mg rivastigmine base, with in vivo release rate of 9.5 mg/24 hours.

What is a substitute for donepezil?

Galantamine (Razadyne) Galantamine works just as well as donepezil and rivastigmine at controlling symptoms of AD. However, folks with kidney impairment or liver disease should not take galantamine. Galantamine comes in immediate-release and extended-release versions.

What is Exelon prescribed for?

Rivastigmine is used to treat confusion (dementia) related to Alzheimer’s disease and to Parkinson’s disease. Rivastigmine does not cure either of these diseases, but it may improve memory, awareness, and the ability to perform daily functions.

Does Exelon cause insomnia?

The most common adverse reactions in patients administered EXELON PATCH in the controlled clinical trial, defined as those occurring at a frequency of at least 5% in the 13.3 mg/24 hours EXELON PATCH arm and at a frequency higher than in the 4.6 mg/24 hours EXELON PATCH were application site erythema, fall, insomnia.

Is there a generic for Exelon Patch?

Mylan has launched Rivastigmine Transdermal System, a generic version of Novartis’ Exelon Patch, for the treatment of patients suffering from dementia in the US.

Can Exelon patch be cut in half?

Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and hairless skin area on your upper or lower back, upper arm, or chest. Do not put the patch over rashes, cuts, or irritated skin.

Can you overdose on Exelon Patch?

Overdose symptoms may include severe nausea, vomiting, salivation, sweating, slow heartbeats, weak or shallow breathing, fainting, or seizure (convulsions).

Can you cut an Exelon patch in half?

How do I switch from Exelon capsules to Exelon patch?

Patients treated with Exelon Capsules or Oral Solution may be switched to EXELON PATCH as follows: A patient who is on a total daily dose of <6 mg of oral rivastigmine can be switched to the 4.6 mg/24 hours EXELON PATCH. A patient who is on a total daily dose of 6 mg to 12 mg of oral rivastigmine can be switched to the 9.5 mg/24 hours EXELON PATCH.

What dose of Exelon patch should I take for hepatic impairment?

Consider using the 4.6 mg/24 hours EXELON PATCH as both the initial and maintenance dose in patients with mild (Child-Pugh score 5 to 6) to moderate (Child-Pugh score 7 to 9) hepatic impairment [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)].

What is the recommended dosage of Exelon oral solution and capsules?

The recommended dosage of EXELON Oral Solution and Capsules in Alzheimer’s disease is 6 mg to 12 mg per day, administered twice a day (daily doses of 3 mg to 6 mg twice a day). There is evidence from the clinical trials that doses at the higher end of this range may be more beneficial.

How often can you take Exelon patch for Alzheimer’s disease?

Severe Alzheimer’s Disease. The effective dosage of EXELON PATCH in patients with severe Alzheimer’s disease is 13.3 mg/24 hours administered once per day; replace with a new patch every 24 hours.