How do you give gentamicin IV?
How do you give gentamicin IV?
Gentamicin when given intravenously should be injected directly into a vein or into the drip set tubing over no less than three minutes. If administered by infusion, this should be over no longer than 20 minutes and in no greater volume of fluid than 100 ml.
Should IV gentamicin be diluted?
Injection, USP – 80 mg/2 mL – (40 mg/mL as Gentamicin) FOR INTRAVENOUS INFUSION OR INTRAMUSCULAR INJECTION – CAUTION: MUST BE DILUTED FOR INTRAVENOUS USE.
Can gentamicin injection be given IV?
Gentamicin injection comes as a liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle). When gentamicin is injected intravenously, it is usually infused (injected slowly) over a period of 30 minutes to 2 hours once every 6 or 8 hours.
How is gentamicin usually dosed?
Gentamicin is normally given by IM injection. Intravenous administration may be used for particular indications when the IM route is not appropriate The dosage is the same for either route of administration.
How long does it take for gentamicin to work?
Your eye should start to feel better within a few days. Even when your eye appears normal again, there may still be some germs present. It is important to continue to use gentamicin for a further 48 hours once your eye appears normal. This will help to make sure that all the germs (bacteria) have been killed.
How is gentamicin calculated?
The dose is calculated using these assumptions:
- CrCl > 40ml/min at 5mg/kg dose to a maximum of 500mg.
- CrCl 10-40ml/min at 3mg/kg dose to a maximum of 300mg.
- CrCl <10ml/min at 1mg/kg dose to a maximum of 120mg.
- Round the dose up or down to the nearest 20mg increment for doses less than 200mg and 40mg above this.
How long is gentamicin IV good for?
If possible, the duration of therapy should be limited to 7 – 10 days (see section 4.2). – Avoid therapy with aminoglycosides immediately subsequent to previous aminoglycoside treatment; if possible, there should be an interval of 7 – 14 days between treatments.
What is gentamicin used for in animals?
Gentamicin is an aminoglycoside antibiotic indicated for the treatment of a variety of bacterial infections. It is normally used as the sulphate salt. In veterinary medicine gentamicin is used mainly as a solution for injection for pigs, cattle and horses and as an oral solution for poultry.
How much gentamicin do you give a 10 year old?
The dosage of gentamicin necessary to produce mean peak serum concentrations between 4 mug/ml and 6 mug/ml was 60 mg/m2 per dose for all age groups or 2.5 mg/kg per dose for ages one-half to five years, 2.0 mg/kg per dose for ages five to 10 years, and 1.5 mg/kg per dose for ages greater than 10 years. Publication types
How do you administer gentamicin IV?
For intermittent intravenous administration, a single dose of Gentamicin Injection may be diluted in 0.9% Sodium Chloride Injection or in 5% Dextrose Injection. The solution may be infused over a period of one-half to two hours. The recommended dosage for intravenous and intramuscular administration is identical.
What is the recommended dosage of gentamicin sulfate for adults?
Adults: The recommended dosage of gentamicin sulfate for patients with serious infections and normal renal function is 3 mg/kg/day, administered in three equal doses every eight hours (TABLE 1).
What is the pharmacokinetics of gentamicin in children and adults?
Pharmacokinetics of gentamicin in children and adults Peak concentrations and half-life of gentamicin in serum were measured after 140 intravenous and 13 intramuscular doses in 52 children and 17 adults with normal levels of creatinine in serum.
