How does del Nido work?

How does del Nido work?

The del Nido cardioplegia is delivered with 20% by volume fully oxygenated patient blood, which supports aerobic metabolism for a finite period of time and provides buffering properties to promote anaerobic glycolysis as well.

How does Custodiol cardioplegia work?

Custodiol® solution, also called histidine-tryptophan-ketoglutarate (HTK) or Bretschneider’s solution, is a particular kind of long-acting intracellular crystalloid cardioplegia (CCP) that differs from other extracellular cardioplegic solutions because of its low sodium and potassium content that induce the diastolic …

When should I Redose del Nido cardioplegia?

A multitude of studies have demonstrated equivalent myocardial protec- tion compared with conventional cold blood cardioplegia in adult cardiac surgery, with the advantage of a single dosing regimen. Expert opinion suggests redosing if the ischemic time is likely to extend much beyond 90 mi- nutes.

What type of cardioplegia is del Nido?

Del Nido cardioplegic solution (DNC), a blood-and-crystalloid solution, is used as a single-dose antegrade infusion to induce rapid cardiac arrest and provide at least 90 minutes of myocardial protection in neonatal heart surgery.

What is Custodiol solution?

Custodiol is an intracellular crystalloid cardioplegic solution used by some centres for myocardial protection in complex cardiac surgery and for organ preservation in transplant surgery.

What are types of cardioplegia?

One of the most important myocardial protection techniques is cardioplegia – indirect or direct administration of cardioplegic solution to the coronary arteries. Both crystalloid cardioplegia and blood cardioplegia are widely used in pediatric cardiac surgery [1–3].

What is Microplegia?

Microplegia (whole blood cardioplegia with reduced volume) retains all the advantages of blood cardioplegia (such as superior oxygen-carrying capacity, better osmotic properties and antioxidant capability, etc.) without the potential disadvantages of hemodilution (such as myocardial edema).

What are the types of cardioplegia?

What is cardioplegia solution?

Cardioplegia Solution A is a sterile, non-pyrogenic solution for cardiac perfusion in a Viaflex bag. It is used to induce cardiac stasis and to protect the myocardium during open-heart surgery.

Where is cardioplegia injected?

The anterograde cardioplegia is inserted in the proximal aorta and contains three lumens: one to administer the cardioplegia, another for suctioning, and the third to measure intraluminal pressure.

How do you administer cardioplegia?

Anterograde cardioplegia is administered into a small cannula placed in the ascending aorta or directly into the coronary ostia. Retrograde cardioplegia is delivered through a catheter placed through the right atrium into the coronary sinus. Cardioplegia is then delivered into the venous system of the heart.

What is buckberg cardioplegia?

Modified Buckberg cardioplegia is a dextrose-based solution in normal saline with potassium chloride as the depolarizing agent, tromethamine as the buffer, and citrate phosphate double dextrose as a calcium chelator and delivered 4:1 oxygenated patient’s blood to crystalloid.