How effective is the pneumococcal pneumonia vaccine?
How effective is the pneumococcal pneumonia vaccine?
Overall, the vaccine is 60% to 70% effective in preventing invasive disease caused by serotypes in the vaccine. PPSV23 shows reduced effectiveness among immunocompromised persons; however, CDC recommends PPSV23 for these groups because of their increased risk of IPD.
Is there a titer for pneumococcal vaccine?
Interpretation of the antibody response to the 23-valent pneumococcal vaccine is straightforward if the preimmunization titer for a given serotype is less than 1.3 μg/mL and the postimmunization titer is 1.3 μg/mL or greater….TABLE III.
| Serotype | OR | Preimmunization titer value (μg/mL) |
|---|---|---|
| 19F | 0.16 | 8.7 |
| 23F | 0.06 | 5.5 |
Can you still get pneumonia if you had a pneumonia shot?
No vaccine is perfect, so it is still possible to get pneumococcal pneumonia (pneumococcus is the bacteria responsible for the most common and one of the most serious types of pneumonia) after vaccination. There are many other types of pneumonia caused by organisms other than the one covered by the vaccine.
When is pneumococcal vaccine recommended?
CDC recommends routine pneumococcal polysaccharide vaccination for: All adults 65 years or older. People 2 through 64 years old with certain medical conditions. Adults 19 through 64 years old who smoke cigarettes.
How long do pneumococcal antibodies last?
either for the number of serotypes or the magnitude of response in units of concentration. Serotype-specific antibodies may persist for up to 10 years following immunization or infection. and the database of IgG antibody concentrations to different serotypes is incomplete.
Is there a lifetime pneumococcal vaccine?
CDC recommends some adults receive up to 3 doses of PPSV23 in a lifetime. Adults who have immunocompromising conditions should receive two doses of PPSV23, given 5 years apart, before age 65 years.
