How fast does hypertrophic cardiomyopathy progress?
How fast does hypertrophic cardiomyopathy progress?
Maron and Spirito8 masterfully described this process in 1998: “…the typical clinical profile of the individual patient with HCM evolving through the end-stage emerges as that of a young or middle-aged adult (age 20–40 years) in whom accelerated clinical deterioration occurs over approximately 5 to 6 years.
Does hypertrophic cardiomyopathy get worse over time?
HCM is a chronic disease that can get worse over time. This can lead to poorer function and quality of life, long-term complications and more financial and social burden. People with HCM often need to make lifestyle changes, such as limiting their activity, to adjust for their disease.
How long can a person live with a stiff heart?
Prognosis in patients with cardiac amyloidosis depends on the subtype. Amyloid light-chain amyloidosis has a poor prognosis with median survival of 13 months without treatment. After the onset of CHF in AL amyloidosis, median survival is only six months.
What are the mortality rates for HCM?
Hypertrophic cardiomyopathy (HCM) is a genetically transmitted disease with a variable clinical course and outcome. In many series, annual death rates are as high as 3–6%,1,2,3,4 but recent studies from centres in Europe and the USA report a substantially better prognosis with overall mortality of 1% or less.
What are the complications of hypertrophic cardiomyopathy (HCM)?
Many people with hypertrophic cardiomyopathy (HCM) don’t experience significant health problems. But some people experience complications, including: Atrial fibrillation.
What are the signs and symptoms of hereditary heart failure (HCM)?
Some people who have HCM have no signs or symptoms, and the disease doesn’t affect their lives. Others have severe symptoms and complications. They may have shortness of breath, serious arrhythmias or an inability to exercise.
What is the rate of incidence of sudden cardiac death with HCM?
Sudden cardiac death is estimated to occur in about 1 percent of people with HCM each year. Hypertrophic cardiomyopathy can cause heart-related sudden death in people of all ages, but the condition most often causes sudden cardiac death in people under the age of 30.
What is the difference between hypertrophic and nonobstructive HCM?
Most people with HCM have this type. In nonobstructive HCM, the heart’s main pumping chamber still becomes stiff. This limits how much blood the ventricle can take in and pump out, but blood flow is not blocked. Some people with hypertrophic cardiomyopathy don’t have symptoms.
