How is Advate produced?
How is Advate produced?
ADVATE is containing recombinant human antihaemophilic factor VIII (rFVIII; INN: octocog alfa), which is synthesised by a genetically engineered Chinese hamster ovary (CHO) cell line.
How long does Antihemophilic Factor last?
ADVATE should be refrigerated (2° – 8°C [36° – 46°F]) in powder form. ADVATE may be stored at room temperature (up to 30°C [86°F]) for a period of up to 6 months not to exceed the expiration date.
How much does recombinant cost?
| Product (Manufacturer) | Source | Average Cost Per Dose ($)a,b |
|---|---|---|
| Recombinate® (Baxter Hyland/Immuno) | Recombinant | 4,480 |
| Kogenate FS® (Bayer) | Recombinant | 4,130 |
| Helixate FS® (Aventis Behring) | Recombinant | 4,130 |
| Refacto® (Genetics Institute) | Recombinant | 4,760 |
Is advate a blood product?
In 2003, ADVATE became the first recombinant factor VIII treatment free of blood-based additives. Since then, TAKEDA has made advancements with flexible dosing options, reconstitution with BAXJECT® system, and the introduction of myPKFiT® for PK-guided personalized dosing.
Who makes Kovaltry?
Bayer, the Bayer Cross, Kogenate, Kovaltry and Jivi are registered trademarks of Bayer. Access Services by Bayer is a trademark of Bayer.
What are Antihemophilic agents?
These agents are used to control bleeding in hemophilia B or FIX deficiency and to prevent and/or control bleeding in patients with hemophilia A and inhibitors to FVIII. These are used to control bleeding in mild hemophilia and in some forms of von Willebrand disease.
How much does Eloctate cost?
The cost for Eloctate intravenous powder for injection recombinant fc fusion protein is around $12 for a supply of 1 powder for injection, depending on the pharmacy you visit….Intravenous Powder For Injection.
| Quantity | Per unit | Price |
|---|---|---|
| 1 | $11.90 | $11.90 |
Is advate a biologic?
Approval Status: Approved by the U.S. FDA on July 25, 2003. Chemical/Biological Nature: ADVATE is the molecularly engineered human Factor VIII glycoprotein consisting of 2,332 amino acids.
Who makes Kogenate?
Authorisation details
| Publication details | |
|---|---|
| Marketing-authorisation holder | Bayer AG |
| Revision | 30 |
| Date of issue of marketing authorisation valid throughout the European Union | 04/08/2000 |
| Contact address | Bayer AG 51368 Leverkusen Germany |
