How is HIT treated?

How is HIT treated?

Treatment of HIT entails immediate withdrawal of all heparin, including heparin-containing flushes and catheters. Heparin cessation alone, however, is often insufficient to prevent thrombosis.

What does HIT stand for in healthcare?

Health information technology
Health information technology (HIT) is defined as “the application of information processing involving both computer hardware and software that deals with the storage, retrieval, sharing, and use of health care information, data, and knowledge for communication and decision making” [1].

Is HIT treatable?

Treatment of HIT should be initiated based on clinical suspicion and must never be delayed pending laboratory confirmation of HIT. A direct thrombin inhibitor, such as lepirudin, danaparoid or argatroban, is considered the agent of choice for treatment of HIT.

Does HIT cause bleeding?

Unlike other forms of thrombocytopenia, HIT is generally not marked by bleeding; instead, venous thromboembolism (eg, deep venous thrombosis, pulmonary embolism) is the most common complication. Less often, arterial thrombosis (eg, myocardial infarction) may occur.

Can you give platelets in HIT?

Platelet transfusions should be avoided in HIT, as they may increase the thrombogenic effect.

What is hit stand for?

HIT

Acronym Definition
HIT Health Information Technology
HIT Healthcare Information Technology
HIT High Intensity Training (weight lifting)
HIT High Intensity Training

Is HIT genetic?

Although several studies have identified genetic polymorphisms such as the Fc receptor RIIA (FCGR2A) –H131R and Fc receptor RIIIA (FCGR3A) –F158V polymorphisms(9–13) associated with HIT, none have identified genetic risk factors that can reliably predict HIT.

How do you test for HIT?

Diagnosis of HIT is based on clinical assessment and laboratory results. Primary laboratory tests for HIT include immunologic assays, such as an enzyme-linked immunosorbent assay (ELISA), and functional, platelet-activation assays, such as the serotonin release assay (SRA).

Does HIT cause blood clots?

HIT happens when your body’s immune system reacts to heparin. This causes changes in your blood. Some people have no symptoms of HIT. But it may cause a dangerous clot to form in blood vessels.

What are the warning signs of HIT?

What Are the Symptoms of HIT?

  • Skin tenderness.
  • Swelling.
  • Skin that’s warm to the touch.
  • Shortness of breath.
  • Change in heart rate.
  • Sharp pain in your chest.
  • Dizziness.
  • Anxiety.

Can enoxaparin cause hit?

Heparin-like medications (such as enoxaparin) may also cause a serious problem known as heparin-induced thrombocytopenia (HIT). HIT is a reaction to heparin (or heparin-like medications) in which the body develops antibodies to the medication.

What are the complications of hit?

Fall in platelet count typically starting within hours after initiation of heparin

  • Thrombocytopenia is severe and frequently results in bleeding
  • Thrombosis in HIT is associated with a mortality of approximately 20-30%
  • Obstetric patients are particularly at risk of developing thrombotic complications
  • What is hit syndrome?

    The existence of spontaneous heparin-induced thrombocytopenia (HIT) syndrome (or autoimmune HIT), defined as a transient prothrombotic thrombocytopenic disorder without proximate heparin exposure serologically indistinguishable from HIT, is controversial.

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