How many genes are in HCMV?
How many genes are in HCMV?
HCMV genes related to immunomodulation and apoptosis are also determinants of virus survival time. A total of 57 genes are related to immune regulation, whereas 14 are related to apoptosis.
What kind of genome does HCMV have?
Human cytomegalovirus (HCMV; species Human herpesvirus 5) has the largest genome of any known human virus, at 236 kbp in size (Dolan et al., 2004). The genome is a linear, double-stranded DNA molecule consisting of two unique regions, each flanked by inverted repeats.
How many CMV strains are there?
Forty-six HCMV strains, consisting of 2 laboratory strains, Towne and AD169, and 44 wild-type strains, isolated from 28 children and the mother of one congenitally infected child, were analyzed.
How does ganciclovir work?
Ganciclovir works by slowing the growth of the CMV virus. It helps control CMV retinitis and decrease the risk of blindness. It also helps prevent the spread of infection to other areas of the body.
Can CMV virus be cured?
CMV spreads from person to person through body fluids, such as blood, saliva, urine, semen and breast milk. There is no cure, but there are medications that can help treat the symptoms.
How common is CMV in adults?
Cytomegalovirus (CMV) is a virus related to the herpes virus. It is so common that almost all adults in developing countries and 50% to 85% of adults in the United States have been infected. Usually CMV is a mild disease that does not cause any serious problems in healthy children and adults.
What does ul 746-b mean?
UL 746-B: Standard for Polymeric Materials – Long Term Property Evaluations 3.1 Long Term tests refer to the expected length of time for the test to be performed. This usually means the test specimens are to be tested are to undergo some length of thermal aging prior to testing.
What is ul 746A test for polymers?
UL 746A: Standard for Polymeric Materials – Short Term Property Evaluations 2.1 Short Term tests refer to the expected length of time for the test to be performed. This usually means the test specimens are to be tested in the “as made” condition.
What are the requirements for UL 746B thermal aging?
For UL 746B tests the general requirements are for thermal aging to be started at four or more elevated temperatures. The most common minimum length of time for which the thermal aging is to be conducted is 5000-hours.
What are the UL standards for evaluation of polymeric materials?
One of the most referenced Standards for evaluation of Polymeric Materials is the UL 746 series. [ Polymeric materials can also be referred to as plastics.] The series consist of 6 linked Standards. UL 746A: Standard for Polymeric Materials – Short Term Property Evaluations