How much does metyrapone cost?
How much does metyrapone cost?
Metopirone (metyrapone) is a member of the adrenal corticosteroid inhibitors drug class and is commonly used for Diagnosis and Investigation….Oral Capsule.
| Quantity | Per unit | Price |
|---|---|---|
| 18 | $34.15 | $614.72 |
How long does Metyrapone take to work?
Metyrapone, sold under the brand name Metopirone, is a potent inhibitor of the 11-beta-hydroxylase enzyme, which plays a key role in cortisol synthesis. This therapy is fast-acting, leading to a reduction in cortisol levels just 30 minutes after a single dose.
How does metyrapone work?
Metyrapone blocks cortisol steroidogenesis by acting as a reversible inhibitor of 11β-hydroxylase. This stimulates adrenocorticotropic hormone (ACTH) secretion, which in turn increases plasma 11-deoxycortisol levels.
What are the side effects of metyrapone?
Nausea, upset stomach, headache, dizziness, or drowsiness may occur. If any of these effects persist or worsen, tell your doctor promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
Why does Metyrapone cause hypertension?
Metyrapone, another steroidogenesis inhibitor that acts by inhibiting 11-beta-hydroxylase activity, causes an increase in intermediates with mineralocorticoid activity leading to a potential worsening in hypertension and hypokalemia.
Is metyrapone over the counter?
Metyrapone may also be used for other conditions as determined by your doctor. Metyrapone is available only with your doctor’s prescription.
What kind of drug is metyrapone?
Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
What is metyrapone test?
The metyrapone stimulation test is based upon the principle that decreasing serum cortisol concentrations normally produces an increase in corticotropin (ACTH) secretion due to a decrease in glucocorticoid negative feedback. The test is performed primarily to detect partial defects in pituitary ACTH secretion.
Is Metyrapone a steroid?
Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
What is the metyrapone test?
