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How safe is Januvia?

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How safe is Januvia?

Overall safety results for Januvia were announced in June 2015 during the American Diabetes Association Scientific Sessions and showed no CV risk among a diverse group of patients taking the drug. A secondary analysis found that the drug did not increase the risk for heart failure among the T2D group.

Does metformin cause pancreatitis?

As any other medication, Metformin is associated with undesirable side effects and it has been reported in few cases to cause lactic acidosis and pancreatitis.

Can liraglutide cause pancreatitis?

The watchdog group Public Citizen has conducted its own analysis of FDA adverse event reports and concluded that the type 2 diabetes drug liraglutide (Victoza) likely causes pancreatitis, the group said.

What are the contraindications of Januvia?

Who should not take JANUVIA?

  • low blood sugar.
  • acute inflammation of the pancreas.
  • chronic inflammation of the pancreas.
  • chronic kidney disease stage 3B (moderate)
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • kidney disease with likely reduction in kidney function.

What drug can replace Januvia?

Alternatives to Januvia

  • linagliptin (Tradjenta)
  • metformin (Glucophage, Glucophage XR, Fortamet, Glumetza)
  • empagliflozin (Jardiance)
  • canagliflozin (Invokana)
  • saxagliptin (Onglyza)
  • alogliptin (Nesina)
  • glipizide (Glucotrol and Glucotrol XL)
  • sitagliptin and metformin hydrochloride (Janumet)

Does Januvia hurt your kidneys?

They may also adjust the dosage of your diabetes medications. It’s not clear whether Januvia causes kidney problems. No clinical studies have linked the use of Januvia to kidney problems. But some people have reported kidney problems after taking Januvia, including kidney failure.

Does Januvia cause cancer?

Experts are concerned that long-term treatment with Januvia could lead to low-level, chronic inflammation in the pancreas, which could lead to pancreatic cancer. Furthermore, in 2011, researchers from UCLA linked Januvia to a 2.7-fold increased risk of pancreatic cancer, based on an analysis…

Can Januvia cause hemorrhagic pancreatitis?

The History of Januvia. As early as 2009, The Food and Drug Administration identified nearly 90 cases of pancreatitis involving Janumet and Januvia between October 2006 and February 2009 alone. Two of these cases involved necrotizing and hemorrhagic pancreatitis.

Are there any lawsuits against the manufacturers of Januvia?

One of the cases names the manufacturers of Bydureon, Victoza, and Tradjenta, in addition to Januvia, Janumet and Byetta. Another lawsuit was brought by the daughter of a man who also passed away after being diagnosed with pancreatic cancer. The Ohio man was first prescribed to Byetta in 2007, and died in 2011.

What are the contraindications for Januvia (sagliptin)?

Before taking Januvia or its generic form sitagliptin, you need to discuss with your doctor. any contraindicated condition you had or currently have including: This is because Januvia is known to increase the potential risk of developing life-threatening pancreatitis when the pancreas inflames and become swollen.

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