Is amiodarone an antiarrhythmic drug?
Is amiodarone an antiarrhythmic drug?
However, its pronounced antiarrhythmic effects redirected its use and amiodarone has become a widely used class III anti-arrhythmic drug. Compared to other antiarrhythmic drugs, it is more effective in treating both supraventricular and ventricular arrhythmias.
Is amiodarone a beta blocker?
Amiodarone is a coronary and peripheral vasodilator (1). Metoprolol is a selective beta1-blocker and exerts a slight vasoconstrictor effect on coronary arteries due to its lack of beta2 stimulation (1).
Is amiodarone a CCB?
Amiodarone possesses multiple pharmacologic properties, including peripheral and coronary vasodilatation, negative inotropy, and negative chronotropic and dromotropic effects. These properties are shared by the group of drugs termed calcium channel blockers.
Is amiodarone an agonist?
Amiodarone is a noncompetitive antagonist of alpha- and beta-adrenergic receptors. It is a type III antiarrhythmic agent and causes prolongation of the action potential of atrial and ventricular tissue. The drug is incompletely and variably absorbed following oral administration; bioavailability ranges from 22 to 86%.
Is amiodarone a Class 1 antiarrhythmic?
Although amiodarone is considered a class III anti-arrhythmic agent, it also has class I, II, IV actions, making it a unique and effective anti-arrhythmic agent.
Is amiodarone a potassium channel blocker?
Amiodarone is a potent antiarrhythmic that has properties of all four Vaughan Williams classes (sodium channel blocker, potassium channel blocker, calcium channel blocker, beta-blocker).
What drug can replace amiodarone?
Dronedarone has been viewed as a potential therapeutic alternative for amiodarone because of a lower risk for pulmonary, thyroid, and dermatologic adverse effects. Compared with amiodarone, dronedarone has poor bioavailability and a shorter terminal disposition half-life, which dictates a twice-daily dosing regimen.
What class is procainamide?
Procainamide is a medication used to manage and treat ventricular arrhythmias, supraventricular arrhythmias, atrial flutter/fibrillation, and Wolf-Parkinson-White syndrome. It is in the antiarrhythmic Agent Class 1A class of medications.
How is amiodarone supplied?
Add 3 mL of Amiodarone HCl Injection (150 mg) to 100 mL D5W (concentration = 1.5 mg/mL). Infuse 100 mL over 10 minutes. Followed by Slow: 360 mg over the NEXT 6 hours (1 mg/min).
What is the chemical name for amiodarone?
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
Amiodarone/IUPAC ID
What is a Class 5 antiarrhythmic?
Class 5 antiarrhythmic drugs are a miscellaneous group of medications that do not belong to a traditional class of antiarrhythmics. These drugs have varied mechanisms of action and uses. The medications in this class are digoxin, adenosine, Mg sulfate, and atropine.
What is a Class III antiarrhythmic?
Class 3 antiarrhythmics are drugs that block cardiac tissue K channels. The medications in this class include amiodarone, dronedarone, sotalol, ibutilide, dofetilide, and bretylium. The main mechanism of action includes blocking the cardiac K channels to prolong repolarization.
What are the symptoms of amiodarone toxicity?
What are symptoms of lithium toxicity? Lithium toxicity: Lithium can cause nausea,vomiting,diarrhea,dizziness,muscle weakness,and fatigue.
What are the classifications of medication?
Analgesics
