Is arachidonic acid supplement safe?

Is arachidonic acid supplement safe?

then you should probably stay away from it since it can be pro-inflammatory. Furthermore, if you suffer from diabetes, asthma, high blood pressure, high cholesterol, heart disease, are pregnant, or are suffering from any inflammatory disease you should not supplement arachidonic acid in your diet.

Does arachidonic acid help with muscle growth?

Furthermore, recent evidence suggests that the prostaglandin isomer PGF2a has a potent ability to stimulate muscle growth. As such, arachidonic acid is a regulator of localized muscle inflammation, and may be a central nutrient controlling the intensity of the anabolic/tissue-rebuilding response to weight training.

What are sources of arachidonic acid?

Arachidonic acid is obtained from food such as poultry, animal organs and meat, fish, seafood, and eggs [2], [3], [4], [5], and is incorporated in phospholipids in the cells’ cytosol, adjacent to the endoplasmic reticulum membrane that is studded with the proteins necessary for phospholipid synthesis and their …

Is arachidonic acid inflammatory?

4.3 Arachidonic acid AA, a polyunsaturated fatty acid present in the phospholipids of cell membrane, is an important inflammatory mediator involved in many molecular and cellular functions under physiological and pathological conditions (Meves, 2008).

What is arachidonic acid metabolism?

Arachidonic acid metabolism provides a pathway for the generation of diverse, fast-acting, short-lived signaling molecules. Cytosolic phospholipase A2 releases arachidonic acid from the phospholipid pool in cellular membranes.

What is arachidonic acid supplement?

Arachidonic acid (ARA), an omega-6 polyunsaturated fatty acid (PUFA), is the metabolic precursor to the eicosanoid family of lipid mediators. Eicosanoids have potent pro-inflammatory actions, but also act as important autocrine/paracrine signaling molecules in skeletal muscle growth and development.

Is arachidonic acid pro inflammatory?

Arachidonic acid is metabolized to both proinflammatory and anti-inflammatory eicosanoids during and after the inflammatory response, respectively. Arachidonic acid is also metabolized to inflammatory and anti-inflammatory eicosanoids during and after physical activity to promote growth.

Where does arachidonic acid come from?

Arachidonic acid in the human body usually comes from dietary animal sources (meat, eggs) or is synthesized from linoleic acid. Arachidonic acid is not one of the essential fatty acids. However, it does become essential if a deficiency in linoleic acid exists or if there is an inability to convert linoleic acid to arachidonic acid occurs.

What are the health effects of arachidonic acid supplementation?

Health effects of arachidonic acid supplementation. Arachidonic acid supplementation in daily doses of 1,000–1,500 mg for 50 days has been well tolerated during several clinical studies, with no significant side effects reported.

Is arachidonic acid a polyunsaturated fatty acid?

Abstract It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its status of polyunsaturated fatty acid essential for normal health.

How many eggs do you need to eat to get arachidonic acid?

One capsule of Enhanced Labs Arachidonic Acid contains 350mg of arachidonic acid. You would have to eat 4,730 whole eggs to get the same amount of arachidnic acid!