Is carbachol a cholinergic agonist?
Is carbachol a cholinergic agonist?
Carbachol, also known as carbamylcholine and sold under the brand name Miostat among others, is a cholinomimetic drug that binds and activates acetylcholine receptors. Thus it is classified as a cholinergic agonist.
What is carbamoylcholine (carbachol)?
Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. 2 Carbamoylcholine was initially used as a treatment for migraines, 6 induction of diuresis, 7 and other parasympathetic effects.
What are the contraindications for the use of carbachol?
Use of carbachol, as well as all other muscarinic receptor agonists, is contraindicated in patients with asthma, coronary insufficiency, gastroduodenal ulcers, and incontinence. The parasympathomimetic action of this drug will exacerbate the symptoms of these disorders.
Is carbachol a strong promoter of ICC activity?
A recent review indicates that carbachol is a strong promoter of ICC activity, which is mediated through the calcium-activated chloride channel, anoctamin 1.
