Is cumene a carcinogen?
Is cumene a carcinogen?
Animal studies have reported increased liver, kidney, and adrenal weights from inhalation exposure to cumene. EPA has classified cumene as a Group D, not classifiable as to human carcinogenicity. cumene Computed by Lexichem TK 2.7.0 (PubChem release 2021.05.07)
What is the chemical name of cumene?
Cumene is an alkylbenzene that is benzene carrying an isopropyl group. Cumene is used in a variety of petroleum products. Acute (short-term) inhalation exposure to cumene may cause headaches, dizziness, drowsiness, slight incoordination, and unconsciousness in humans.
How is cumene absorbed and excreted from the body?
Cumene is absorbed readily by the mammalian system and oxidized at the side chain, one of the metabolites being the dimethylphenylcarbinol glucuronide. In rabbits, 90% of a 2 mL oral dose was accounted for as side-chain oxidation products of cumene, which were excreted as glucuronide conjugates.
https://www.youtube.com/watch?v=QYJPAeLAZW8
Cumene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. Cumene caused tumors at several tissue sites, including lung and liver in mice and kidney in male rats.
Is cumene isopropyl benzene?
Cumene is a common name for isopropylbenzene, an organic compound.
isopropylbenzene
Cumene (isopropylbenzene) is an organic compound that is based on an aromatic hydrocarbon with an aliphatic substitution. It is a constituent of crude oil and refined fuels….Cumene.
| Names | |
|---|---|
| Preferred IUPAC name (Propan-2-yl)benzene | |
| Other names Isopropylbenzene Cumol (1-Methylethyl)benzene | |
| Identifiers | |
| CAS Number | 98-82-8 |
What does cumene smell like?
Cumene, also known as isopropylbenzene, 2-phenylpropane, or (1-methylethyl) benzene, is a colorless, volatile liquid with a gasoline-like odor. It is a natural component of coal tar and crude oil, and also can be used as a blending component in gasoline.
How do you get phenol from cumene?
To prepare phenol, cumene is first oxidized in the presence of air of cumene hydro-peroxide. Then, cumene hydroxide is treated with dilute acid to prepare phenol and acetone as by-products.
Is cumene hazardous?
* Exposure can cause headache, dizziness, poor coordination and even passing out. * Cumene Hydroperoxide may cause a skin allergy. If allergy develops, very low future exposure can cause itching and a skin rash. * Cumene Hydroperoxide is a HIGHLY REACTIVE CHEMICAL and a DANGEROUS EXPLOSION HAZARD.
What products contain cumene?
Cumene can be found in crude oil and is a part of processed high-octane gasoline. Cumene is used as thinner for paints, lacquers and enamels. It is also used in the manufacture of other chemicals commonly found in home cleaning products.
Is cumene a phenol?
Starting with the alkylation of benzene with mixture of 1 and 2-butenes, the cumene process produces phenol and butanones.
What is the formula of cumene hydroperoxide?
C9H12O2
Cumene hydroperoxide/Formula
What is cumene reaction?
The cumene process (cumene–phenol process, Hock process) is an industrial process for synthesizing phenol and acetone from benzene and propylene. The term stems from cumene (isopropyl benzene), the intermediate material during the process.
When phenol is prepared from cumene Which of the following is obtained as a byproduct in large quantities?
acetone
Cumene is converted by air oxidation into cumene hydroperoxide,which is converted by aqueous acid into phenol and acetone: Along with the large amount of phenol produced each year, a great deal of acetone is obtained, and this process is one of the prinicipal sources of that compound ,too.
Is cumene toxic to humans?
CUMENE is a clear colorless liquid with an aromatic odor. Flash point 115°F. Less dense than water and insoluble in water. Vapors heavier than air. May be moderately toxic by inhalation, ingestion and skin absorption.
What is the flash point of cumene?
Cumene appears as a clear colorless liquid with an aromatic odor. Flash point 115°F. Less dense than water and insoluble in water. Vapors heavier than air. May be moderately toxic by inhalation, ingestion and skin absorption.
What is the difference between isopropylbenzene and cumene?
Cumene is an alkylbenzene that is benzene carrying an isopropyl group. Isopropylbenzene is found in ceylan cinnamon. Isopropylbenzene is a trace constituent of ginger oil (Zingiber officinale) Cumene is the common name for isopropylbenzene, an organic compound that is an aromatic hydrocarbon.
