Is fixed drug eruption an allergy?

Is fixed drug eruption an allergy?

Fixed drug eruption is a distinctive cutaneous allergic reaction that characteristically recurs at the same site(s) on re-exposure to the medication or other chemical agent.

What is the most common presentation of amoxicillin drug eruption?

Morbilliform or exanthematous This is the most common pattern of drug eruptions; it is the quintessential drug rash. Exanthem is typically symmetric, with confluent erythematous macules and papules that spare the palms and soles. It typically develops within 2 weeks after the onset of therapy.

What are the symptoms of dress syndrome?

DRESS syndrome is characterized by fever, rash, abnormal blood tests, and swollen lymph nodes (small glands that filter foreign substances and contain cells that help the body fight infection). The condition also affects at least one internal organ — most often the liver.

What drugs can cause drug eruption?

The most common drugs that may potentially cause drug eruptions include amoxicillin, trimethoprim sulfamethoxazole, ampicillin, penicillin, cephalosporins, quinidine and gentamicin sulfate.

Can vitamins cause fixed drug eruption?

Drug reactions related to multivitamins are rare and very few cases have been reported. This is a case of a young woman who developed bullous fixed drug eruption to multivitamins.

Do fixed drug eruptions disappear?

Fixed drug eruptions (FDE) are a distinct type of drug eruptions that appear as pruritic, well circumscribed, round or oval-shaped, erythematous macules or edematous plaques, and characteristically recur at the same sites upon re-exposure to the offending drug. They usually resolve spontaneously with hyperpigmentation.

What are the allergic reactions to amoxicillin?

Hives are raised, itchy, welts that usually pop up within hours after taking the medicine. A person may also have symptoms such as trouble breathing or swallowing. If a person has a true allergic reaction to amoxicillin, they should seek emergency medical attention if they are having problems breathing.

Is DRESS syndrome life threatening?

DRESS syndrome is a life-threatening disease with a mortality rate of around 10% [2]. Patients may also suffer morbidities due to DRESS syndrome-related organ damage or due to treatment-related complications.

Is DRESS syndrome an autoimmune disease?

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is associated with long-term autoimmune sequelae. Patients require careful monitoring for autoimmune disease following recovery from DRESS syndrome.

What is bullous eruption?

What are bullous drug eruptions? The term bullous drug eruptions refers to adverse drug reactions that result in fluid-filled blisters or bullae. Blistering can be due to various medications, prescribed or over-the-counter, natural or synthetic.

What is the most common drug induced cutaneous reaction?

Exanthematous drug eruptions, also known as maculopapular drug eruptions, are the most common cutaneous skin reactions and represent approximately 95% of all cutaneous drug eruptions.

What is status asthmaticus in medical practice?

Practice Essentials. Status asthmaticus is considered a medical emergency. It is the extreme form of an asthma exacerbation that can result in hypoxemia, hypercarbia, and secondary respiratory failure. In practice, the role of the physician is to prevent this from happening through patient compliance with controller medications (eg,…

What is the social history of exacerbation of asthma?

The social history may include home characteristics, smoking, workplace or school characteristics, educational level, employment, social support, factors that may contribute to nonadherence of asthma medications, and illicit drug use. The patient’s exacerbation history is important with respect to the following: Usual prodromal signs or symptoms

What are the a stepwise guidelines for the treatment of asthma?

A stepwise (step-up if necessary and step-down when possible) approach to asthma management continues to be used in the current guidelines and is now divided into 3 groups based on age (0-4 y, 5-11 y, 12 y and older). [ 1] For all patients, quick-relief medications include rapid-acting beta 2 agonists as needed for symptoms.

What is the relationship between asthma and wheezing?

In a more severe asthmatic episode, wheezing is also present during inspiration. During a most severe episode, wheezing may be absent because of the severe limitation of airflow associated with airway narrowing and respiratory muscle fatigue. Asthma can occur without wheezing when obstruction involves predominantly the small airways.