Is spindle cell neoplasm a cancer?
Is spindle cell neoplasm a cancer?
Spindle cell sarcoma is a rare malignant (cancerous) tumour which can develop in the bone or soft tissue. It can arise in any part of the body but is most common in the limbs (arms and legs).
What is spindle neoplasm?
Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components.
Is spindle cell cancer curable?
Spindle cell carcinoma (SCC) is a highly malignant pulmonary sarcomatoid carcinoma. There is no standard treatment for this disease, though chemotherapy, surgery and radiation therapy may be considered.
Is neoplasm the same as cancer?
1 Cancer is a neoplasm that can grow rapidly, spread, and cause damage to the body. A malignant neoplasm is cancerous, while a metastatic neoplasm is malignant cancer that has spread to nearby or distant areas of the body.
How long can you live with spindle cell carcinoma?
Median overall survival ranges from 6 to 20 months in surgical series. The main prognostic factor is staging. Metastatic sarcomatoid carcinomas are often treated as other NSCLC, with platinum-based chemotherapy considered standard as first-line treatment.
What are spindle cell neoplasms in the skin?
Spindle cell neoplasms arising in the skin comprise a heterogeneous group of tumors with divergent lineages. Cutaneous spindle cell neoplasms are relatively common and present surgical pathologists with diagnostic challenges. Recognition of their histopathologies is important for correct diagnosis and management.
What are the histologic features of spindle cell tumors of children?
The clinical, histologic, and diagnostic features of the spindle cell tumors of children are summarized in Table 6.1.1. Histologically, calcifying aponeurotic fibroma is characterized by a proliferation of fibrous tissue that tends to simulate fibromatosis ( Figure 6.1.4 ).
What is spindle cell melanoma with S100 protein positive?
Spindle cell melanoma is positive for S100 protein. For malignant spindle cell neoplasms arising in the skin and mucosal sites, suspicion of spindle cell squamous cell carcinoma should be considered in differential diagnosis before diagnosing sarcoma.
What are spindle cell and pleomorphic lipomas?
Spindle cell and pleomorphic lipomas are subcutaneous lesions, which occur mainly in the head and neck region of male patients. Most tumors are asymptomatic and occur in the sixth decade of life. They have a benign behavior and can be conservatively excised.
