What are drug receptors?
What are drug receptors?
Drug Receptors intercaction and Drug antagonism : Dr Rahul Kunkulol’s Power p… 1. Receptor Pharmacology Tulasi Raman.P Moderator: Dr. Kartik Salwe 2. Definition• The term receptor is used in pharmacology to denote a class of cellular macromolecules that are concerned specifically and directly with chemical signaling between and within cells.
How do you increase the biological response of a drug?
Increasing concentrations of the agonist will increase the biological response until there are no more receptors for the agonist to bind or a maximal response has been reached. A partial agonist produces the biological response but cannot produce 100% of the biological response even at very high doses.
What are intracellular receptors?
Intracellular ReceptorsThis nuclear receptor family senses signals fromthe lipid soluble substances (e.g. Vit A & D) andother hormonal substances to influence the geneexpression. 22.
What is the concept of dual nature of receptors?
6. The concept of dual nature of receptors• Receptors usually exists in two conformations – The active (Ra) state – Inactive (Ri) state If Ra and Ri conframations are in equlibrium, the extent to which this equilibrium perturbed shall be determined by the relative affinity of the drug for these two conframations 7.
