What are NBS-LRR genes?

What are NBS-LRR genes?

Nucleotide-binding site–leucine-rich repeat (NBS-LRR) genes are the largest group of plant R genes, and they play important roles in plant defense responses to various pathogens. In this study, 167 NBS-LRR genes were identified from the D. rotundata genome.

Which proteins help in disease resistance?

Most plant disease resistance (R) proteins contain a series of leucine-rich repeats (LRRs), a nucleotide-binding site (NBS), and a putative amino-terminal signaling domain. They are termed NBS-LRR proteins.

What is NB arc?

The NB-ARC domain is a functional ATPase domain, and its nucleotide-binding state is proposed to regulate activity of the R protein. A highly conserved methionine-histidine-aspartate (MHD) motif is present at the carboxy-terminus of ARC2.

What is NB LRR proteins?

NBS-LRR proteins are some of the largest proteins known in plants, ranging from about 860 to about 1,900 amino acids. They have at least four distinct domains joined by linker regions: a variable amino-terminal domain, the NBS domain, the LRR region, and variable carboxy-terminal domains (Figure 1).

Why is eating enough protein important?

Your body needs protein to stay healthy and work the way it should. More than 10,000 types are found in everything from your organs to your muscles and tissues to your bones, skin, and hair. Protein is also a critical part of the processes that fuel your energy and carry oxygen throughout your body in your blood.

Which disease is caused by deficiency of protein?

What Is Kwashiorkor? Kwashiorkor, also known as “edematous malnutrition” because of its association with edema (fluid retention), is a nutritional disorder most often seen in regions experiencing famine. It is a form of malnutrition caused by a lack of protein in the diet.

What are the symptoms of an extreme protein deficiency?

Symptoms of protein deficiency include fatigue, weakness, thinning hair, brittle nails, and dry skin.

What is the size of NBS LRR protein?

NBS-LRR proteins are some of the largest proteins known in plants, ranging from about 860 to about 1,900 amino acids. They have at least four distinct domains joined by linker regions: a variable amino-terminal domain, the NBS domain, the LRR region, and variable carboxy-terminal domains (Figure 1).

What is the function of the amino-terminal domain of LRR proteins?

There is little experimental information on the function of the amino-terminal domain. In animals, the TIR domain is involved in signaling downstream of Toll-like receptors. Many plant NBS-LRR proteins are thought to monitor the status of (‘guard’) targets of pathogen virulence effectors (see below).

Are plant NOD-LRR proteins similar to mammalian Nod proteins?

But although mammalian NOD-LRR proteins have the same tripartite domain organization as plant NBS-LRR proteins, including a nucleotide-binding domain and a LRR domain, the functional similarities between NBS-LRR and mammalian NOD proteins are probably the result of convergent evolution [ 7 ].

Is apoptotic protease activating factor 1 (Apaf-1) a NBS-LRR protein?

The human NOD protein apoptotic protease activating factor 1 (APAF-1) has an NBS domain with greater protein-sequence similarity to plant NBS-LRR proteins than to other mammalian NOD proteins; however, it shares neither the amino-terminal nor the carboxy-terminal LRR domains characteristic of plant NBS-LRR proteins.