What are the ATP IV guidelines?

What are the ATP IV guidelines?

The ATP-IV component of the guideline would address following three critical areas: 1) Evidence supporting LDL-C for secondary prevention; 2) Primary prevention of LDL; and 3) Efficacy and safety of major cholesterol drugs.

What are the new guidelines for statins?

The U.S. Preventive Services Task Force recommends low- to moderate-dose statins in adults ages 40 to 75 who have one or more risk factors for heart and blood vessel disease and at least a 1 in 10 chance of having a cardiosvascular disease event in the next 10 years.

What are the 4 statin groups?

Since the 2013 update, the American College of Cardiology/American Heart Association guidelines for the management of blood cholesterol have identified 4 statin benefit groups: clinical ASCVD, severe hypercholesterolemia (low‐density lipoprotein cholesterol [LDL‐C] ≥190 mg/dL), diabetes mellitus in adults, and those …

What are the latest cholesterol guidelines?

New cholesterol guidelines are helping physicians and their patients take a more proactive — and personalized — approach to cardiovascular risks….How do I know what’s happening in my body?

Desirable Cholesterol Levels
Total cholesterol	Less than 170 mg/dL
High HDL (“good”) cholesterol	35 mg/dL or higher

What is ATP IV?

Appendix D.: Target Lipid Recommendations (ATP-IV) Non-HDL-C is calculated as total cholesterol minus HDL-C . The addition of non- HDL-C to the Lipid Panel reflects the recognition of this calculated value as a predictive factor in cardiovascular disease based on the National Cholesterol Education III studies.

What are moderate-intensity statins?

Moderate-Intensity Statins. • Atorvastatin 10–20 mg. • Rosuvastatin 5–10 mg. • Simvastatin 20–40 mg. • Pravastatin 40–80 mg.

What is perfect HDL cholesterol level?

The ideal HDL level is at least 40 mg/dL in men and at least 50 mg/dL in women.

What level of cholesterol requires medication?

Medication is typically recommended when: your cholesterol levels are high enough to increase your risk for cardiovascular disease (or you already had a cardiovascular event, such as a heart attack or stroke) you have an LDL level greater than 190 milligrams per deciliter (mg/dL)

What is a high-intensity statin?

High-intensity statin was defined as atorvastatin administered at 40–80 mg, rosuvastatin at 20–40 mg, or simvastatin at 80 mg, i.e., medication amounts higher than the standard doses described in recent guidelines [8, 9].

What is moderate intensity statin therapy?

^Moderate Intensity Statin Therapy – defined as dose expected to reduce. LDL-C by 30-50% and includes the following: (1,2) Atorvastatin 10-20mg everyday. Fluvastatin 40mg twice daily. Fluvastatin XL 80mg everyday.

What is the most important cholesterol reading?

HDL (“good” cholesterol) of 50 mg/dL or higher, if you’re a woman, or 40 mg/dL or higher, if you’re a man. Optimal LDL is 100 or lower, says Mosca. If you have other major risk factors, like pre-existing cardiovascular disease or diabetes, your doctor may want your LDL closer to 70.

What is the ATP III?

The Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III, or ATP III) constitutes the National Cholesterol Education Program’s (NCEP’s) updated clinical guidelines for cholesterol testing and manage- ment.

What do the new ATP III guidelines for LDL-C levels tell us?

The new guidelines do not provide ample guidance on evaluating and monitoring efficacy of therapy. ATP III and its 2005 update 3 set a goal for LDL-C at < 100 mg/dL for high-risk patients, especially those with established ASCVD. Patients with diabetes and a 10-year risk greater than 20% further counted as high-risk patients.

What are the ATP III and ACC/AHA guidelines on statin drug therapy?

Both ATP III and ACC/AHA guidelines carried out 10-year risk assessment to guide drug therapy. ATP III recommended consideration of drug therapy when 10-year risk for CHD was ≥ 10%. ACC/AHA set a threshold for statin drugs at 7.5% for ASCVD. Even ≥5% risk was considered a therapeutic option for statin therapy.

What do ATP III and ACC/AHA guidelines tell us about lifestyle intervention?

Both ATP III and ACC/AHA guidelines emphasize the value of lifestyle intervention. An interesting aspect of the ACC/AHA guidelines is that lifestyle is promoted without RCT evidence. In so doing, the new guideline panel broke their own evidence-based rules. Seemingly, these rules are applied only to drug therapy.

What is the ATP III classification of triglycerides?

ATP III Classification of Serum Triglycerides (mg/dL) <150 Normal 150-199 Borderline high 200-499 High ≥500 Very high Treatment of elevated triglycerides (≥150 mg/dL) Primary aim of therapy is to reach LDL goal Intensify weight management Increase physical activity If triglycerides are >200 mg/dL after LDL goal is reached, set