What causes loss of adipose tissue?
What causes loss of adipose tissue?
In most cases, adipose tissue loss begins during puberty. FPL can be associated with a variety of metabolic abnormalities. The extent of adipose tissue loss usually determines the severity of the associated metabolic complications. These complications can include glucose intolerance, hypertriglyceridemia and diabetes.
How many people have Donohue?
Donohue syndrome is estimated to affect less than 1 per million people worldwide. Several dozen cases have been reported in the medical literature.
What is Lawrence disease?
Acquired generalized lipodystrophy (also known as “Lawrence syndrome,” and “Lawrence–Seip syndrome”, abbreviation: AGL) is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs.
Is there a cure for lipodystrophy?
Lipodystrophy is a progressive and life-threatening disease. Currently, there is no cure for lipodystrophy. Metabolic comorbidities must be treated to manage the short- and long-term complications of the disease.
What is congenital generalized lipodystrophy (Berardinelli-Seip)?
Congenital generalized lipodystrophy (also called Berardinelli-Seip congenital lipodystrophy) is a rare condition characterized by an almost total lack of fatty (adipose) tissue in the body and a very muscular appearance. Adipose tissue is found in many parts of the body, including beneath the skin and surrounding the internal organs.
What is congenital generalized lipodystrophy (CGL)?
Congenital generalized lipodystrophy (CGL), also known as Berardinelli-Seip syndrome, is a rare genetic disorder characterized by the near total loss of body fat (adipose tissue) and extreme muscularity that is often present at birth or soon thereafter.
What is the prevalence of lipodystophy?
It is a type of lipodystophy disorder where the magnitude of fat loss determines the severity of metabolic complications. Only 250 cases of the condition have been reported, and it is estimated that it occurs in 1 in 10 million people worldwide.
