What class of drug is trimetazidine?
What class of drug is trimetazidine?
Trimetazidine (l-2,3,4-trimethoxybenzyl piperazine dihydrochloride), a member of the class of 3-ketoacyl coenzyme A thiolase (3-KAT) inhibitors, is a metabolic modulator that improves myocardial energetics at several levels.
What classification of drug best describes Lasix?
Lasix belongs to a class of drugs called Diuretics, Loop.
What is the pharmacological name of Lasix?
Lasix (furosemide) is a loop diuretic (water pill) that prevents your body from absorbing too much salt. This allows the salt to instead be passed in your urine. Lasix is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.
What is the expected pharmacological action of Lasix?
Furosemide works by blocking the absorption of sodium, chloride, and water from the filtered fluid in the kidney tubules, causing a profound increase in the output of urine (diuresis). The onset of action after oral administration is within one hour, and the diuresis lasts about 6-8 hours.
What is the use of trimetazidine?
Trimetazidine is an anti-ischemic agent widely used in the treatment of coronary artery disease.
What is the mechanism of action of trimetazidine?
The best known trimetazidine mechanism of action is its capacity to inhibit β-oxidation of free fatty acid (FFA) [1]. FFA oxidation provides more energy, but it is associated with increased oxygen consumption.
Are there different types of Lasix?
Lasix is available in tablet (20 to 80 mg) and IV forms. Dosage is determined by the patient’s physician and varies according to how much fluid and how fast the fluid should be removed. Patients with poor renal function usually require higher doses; doses in children are weight-based.
What kind of diuretic is furosemide?
Furosemide belongs to a group of medicines called loop diuretics (also known as water pills). Furosemide is given to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions.
What class of diuretic is furosemide?
Furosemide is a type of medicine called a loop diuretic. A diuretic makes your body get rid of extra fluid through your kidneys. A loop diuretic works on a specific part of the kidney called the “loop of Henle” to increase the salt and water you pee out.
Is trimetazidine used in congestive heart failure?
Trimetazidine has been recommended for the treatment of stable coronary artery diseases since 2013, but it has not been recommended for heart failure (Montalescot et al., 2013; Milinković et al., 2016).
What is trimetazidine (Vastarel)?
Trimetazidine is a drug for angina pectoris sold under the brand name Vastarel MR. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France).
Trimetazidine. Trimetazidine is an orally available small molecule compound with anti-ischemic, and potential immunomodulating and antineoplastic properties. Although its exact mechanism is not yet fully elucidated, it is postulated that upon administration, trimetazidine selectively inhibits long-chain 3-ketoacyl coenzyme A thiolase (LC 3-KAT),…
What is trimethoxybenzyl piperazine dihydrochloride?
Trimetazidine (l-2,3,4-trimethoxybenzyl piperazine dihydrochloride), a member of the class of 3-ketoacyl coenzyme A thiolase (3-KAT) inhibitors, is a metabolic modulator that improves myocardial energetics at several levels.
Is tradtrimetazidine (TMZ) a PFOX inhibitor?
Trimetazidine (TMZ) is frequently presented as the archetype of partial fatty acid oxidation (pFOX) inhibitors.
