What does Borrelia burgdorferi do to the body?

What does Borrelia burgdorferi do to the body?

Borrelia burgdorferi is the etiological agent of Lyme disease, a multisystemic, multistage, inflammatory infection resulting in patients experiencing cardiac, neurological, and arthritic complications when not treated with antibiotics shortly after exposure.

Where is bacterium Borrelia burgdorferi found?

Animal studies have shown that Borrelia burgdorferi can be found in many tissues and organs including the skin, joints, heart, brain, bladder and other sites of untreated animals as well as in animals who receive antibiotic treatment (Barthold, 2012, and Embers, Barthold, Borda et. al., 2012).

Is Borrelia a parasite or bacteria?

The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir is a variety of small mammals [1].

Can Borrelia burgdorferi be cured?

Lyme disease is caused by infection with the bacterium Borrelia burgdorferi. Although most cases of Lyme disease can be cured with a 2- to 4-week course of oral antibiotics, patients can sometimes have symptoms of pain, fatigue, or difficulty thinking that lasts for more than 6 months after they finish treatment.

What bacteria is responsible for Lyme disease?

Lyme disease is caused by the bacterium Borrelia burgdorferi and rarely, Borrelia mayonii. It is transmitted to humans through the bite of infected blacklegged ticks.

What does Lyme bacteria feed on?

Lyme disease is caused by the Borrelia burgdorferi bacterium that’s carried by deer, mice and other animals. The tick feeds on the blood of the infected animal and ingests the bacteria, which then lives in the tick’s gut, Rebis explains.

How does Borrelia burgdorferi survive?

Typically, larval ticks become infected with B. burgdorferi by feeding on an infected vertebrate host, often a small mammal. B. burgdorferi survives within the tick midgut (2) as larval ticks molt into nymphs (transstadial passage) and the nymphs wait to feed again, which can include overwintering (4, 5).

Is Lyme disease a bacillus?

Borrelia burgdorferi sensu stricto is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans….

Borrelia burgdorferi
Domain: Bacteria
Phylum: Spirochaetes
Order: Spirochaetales
Family: Spirochaetaceae

Is Borrelia burgdorferi Gram positive or negative?

burgdorferi is known to have an atypical Gram-negative cell membrane (Barbour & Hayes, 1986).

What are the problems with Lyme disease?

Lyme disease also can affect the heart. The most common problem is a very slow heartbeat that leads to fatigue, dizziness and fainting. The heart muscle can also be inflamed, called myocarditis . Lyme disease also can cause pain and swelling of joints.

How to diagnose Lyme disease?

These details are crucial to making a diagnosis of Lyme disease. Symptoms can include: Fever. Rash that may look like a “bull’s-eye”. Headaches. Stiff neck. Facial palsy (Drooping or loss of muscle tone in your face) Severe joint pain or swelling.

What happens if you get Lyme disease?

Untreated, Lyme disease can spread to other parts of your body for several months to years after infection, causing arthritis and nervous system problems. Ticks can also transmit other illnesses, such as babesiosis and Colorado tick fever. The deer tick (Ixodes scapularis) goes through three life stages.

What is the bacteria responsible for Lyme disease?

Ancient evidence of a familiar foe has emerged in a fossil tick infested with what appears to be spirochetes, a group of rotini-shaped bacteria responsible for many human diseases. The spirochetes in question closely resemble those of modern-day Borrelia, the genus responsible for Lyme disease.

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