What does neuronal migration mean?
What does neuronal migration mean?
Neuronal migration is a fundamental process in central nervous system (CNS) development. The assembly of functioning neuronal circuits relies on neuronal migration occurring in the appropriate spatio-temporal pattern. A defect in the neuronal migration may result in a neurological disorder.
What causes neuronal migration?
What causes a neuronal migration disorder? Doctors think that neuronal migration disorders are genetic in that a faulty gene stops the neural circuits forming properly. Some neuronal migration disorders are passed on from parent to child, but most develop as a sporadic genetic fault that just happens.
When does neuronal migration occur?
In the developing brain, neurons must migrate from the areas where they are born to the areas where they will settle into their proper neural circuits. Neuronal migration, which occurs as early as the second month of gestation, is controlled by a complex assortment of chemical guides and signals.
Why are neural connections important?
Every new experience and memory creates connections between neurons, or synapses. These connections enable basic brain functions. Like the foundation of a house, stronger connections early in life lead to more functional brains. Although our genes dictate how brain connections form, experience activates the connection.
What are neuronal migration disorders?
Neuronal Migration Disorders Neuronal migration disorders (NMDs) are a group of birth defects caused by the abnormal migration of neurons in the developing brain and nervous system. In the developing brain, neurons must migrate from the areas where they are born to the areas where they will settle into their proper neural circuits.
How to promote neurons to migrate in the injured brain?
These studies indicated that the persistent and controlled release of growth/trophic factors from biomaterials may be an efficient strategy for promoting neuronal migration in the injured brain. Providing appropriate scaffolds for migrating neurons in the injured brain is another potential strategy for promoting neuronal migration.
Are there distinct modes of migration in the brain?
Regardless of the cell biological mechanisms, distinct modes of migration exist in the embryonic and adult brains, which seem to be adapted to fulfill different functions during evolution.
How do neurons move from one place to another?
In the developing brain, neurons must migrate from the areas where they are born to the areas where they will settle into their proper neural circuits. Neuronal migration, which occurs as early as the second month of gestation, is controlled by a complex assortment of chemical guides and signals.
