What group of antibiotics is trimethoprim?

What group of antibiotics is trimethoprim?

Trimethoprim is a dihydropyrimidine antimicrobial and antiparasitic agent. It is the prototype of a group of nonsulfonamide drugs that inhibit dihydrofolate reductase in bacterial and protozoal cells.

What does it mean to synthesize a drug?

3 the process of producing a compound by a chemical reaction or series of reactions, usually from simpler or commonly available starting materials.

Does trimethoprim have a good selective toxicity?

INTRODUCTION. Sulfonamides and trimethoprim are antimetabolites selectively toxic to microorganisms because they interfere with folic acid synthesis. Sulfonamides continue to be used selectively as individual antimicrobial agents, although resistance is common.

What is the bacterial target of trimethoprim?

Trimethoprim exerts antimicrobial activity by blocking the reduction of dihydrofolate to tetrahydrofolate, the active form of folic acid, by susceptible organisms. It has inhibitory activity for most gram-positive aerobic cocci and some gram-negative aerobic bacilli.

What are the common side effects of trimethoprim?

Diarrhea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What are the side effects of taking trimethoprim?

You’re unlikely to get side effects from trimethoprim. Some people get itching or a skin rash, but this is usually mild and goes away after you stop taking the medicine….Common side effects

• itching or a mild rash.
• feeling or being sick (nausea or vomiting)
• diarrhoea.
• headaches.

How does a synthesis reaction work?

Synthesis reactions are reactions that occur when two different atoms or molecules interact to form a different molecule or compound. Most of the time, when a synthesis reaction occurs, energy is released and the reaction is exothermic.

What kind of chemical reaction is synthesis?

A synthesis reaction is a type of reaction in which multiple reactants combine to form a single product. Synthesis reactions release energy in the form of heat and light, so they are exothermic. An example of a synthesis reaction is the formation of water from hydrogen and oxygen.

What is trimethoprim side effects?

Who should not take trimethoprim?

You should not use trimethoprim if you are allergic to it, or if you have: anemia (low red blood cells) caused by a folate (folic acid) deficiency.

What are the side effects of amoxicillin in humans?

Side Effects of Amoxicillin 1 Amoxicillin side effects. 2 Diarrhea. 3 Stomach upset. 4 Headache. 5 Abnormal taste sense. 6 Skin rash. 7 Vaginal yeast infection. 8 Less common side effects. 9 More amoxicillin resources and information.

What should I do if I have an allergic reaction to amoxicillin?

If a person has a true allergic reaction to amoxicillin, they should seek emergency medical attention if they are having problems breathing. If they can take an antihistamine like diphenhydramine (Benadryl), it may help the itching. They should call their doctor and ask for a prescription for another antibiotic “family” if they are truly allergic.

Does amoxicillin interact with other medications?

Does AMOXICILLIN Interact with other Medications? These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

Is amoxicillin Gram positive or negative?

Amoxicillin covers a wide variety of gram-positive bacteria, with some added gram-negative coverage compared to penicillin. Similar to penicillin, it covers most Streptococcus species and has improved coverage of Listeria monocytogenes and Enterococcus spp.