What is a heterocyclic drug?
What is a heterocyclic drug?
Heterocycles are common fragments of the vast majority of marketed drugs. This is a reflection of the central role that heterocycles play in modern drug design. Heterocycles are common structural units in marketed drugs and in medicinal chemistry targets in the drug discovery process.
What are heterocyclic reactions?
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles.
What is heterocyclic nucleus?
Heterocyclic nucleus plays a fundamental role in the medicinal chemistry and serves as a key template for the development of various therapeutic agents including broad spectrum antibacterial drugs.
What drugs contain heterocyclic rings?
Heterocyclic Compounds, Fused-Ring
| Drug | Drug Description |
|---|---|
| Citalopram | A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. |
| Eletriptan | A triptan used for the treatment of migraines. |
| Moxifloxacin | A fluoroquinolone antibiotic used to treat various bacterial infections. |
What are heterocyclic antidepressants?
The heterocyclic antidepressants, once the mainstay of treatment, include tricyclic, modified tricyclic, and tetracyclic antidepressants. Acutely, these drugs increase the availability of primarily noradrenalin and, to some extent, serotonin by blocking their reuptake in the synaptic cleft.
What are heterocyclic compounds used for?
Heterocyclic compunds have a wide range of application. They are predominantly used as pharmaceuticals, as agrochemicals and as veterinary products. They also find applications as sanitizers, developers, antioxidants, as corrosion inhibitors, as copolymers, dye stuff.
What does heterocyclic mean in chemistry?
heterocyclic compound, also called heterocycle, any of a major class of organic chemical compounds characterized by the fact that some or all of the atoms in their molecules are joined in rings containing at least one atom of an element other than carbon (C).
What is heterocyclic compound give example?
The most common heterocycles are those having five- or six-membered rings and containing heteroatoms of nitrogen (N), oxygen (O), or sulfur (S). The best known of the simple heterocyclic compounds are pyridine, pyrrole, furan, and thiophene.
What is the importance of heterocyclic compound?
What is fused heterocyclic?
• Fused heterocycles are systems constructed by. combining two or more rings. • The rings are fused if they are linked in such a way that. each ring has one common bond (fusion bond) to each. other.
What are examples of heterocyclic antidepressants?
Heterocyclic antidepressants:
- amoxapine (Asendin)
- trazodone hydrochloride (Desyrel)
- maprotiline hydrochloride (Ludiomil)
What are the oldest antidepressants?
Tricyclic antidepressants affect three brain chemicals. They are serotonin, norepinephrine, and dopamine. This is one of the oldest types of antidepressants.
What is the classification of heterocyclic compounds?
Classification. Although heterocyclic chemical compounds may be inorganic compounds or organic compounds, most contain at least one carbon. While atoms that are neither carbon nor hydrogen are normally referred to in organic chemistry as heteroatoms, this is usually in comparison to the all-carbon backbone.
Can a carbocyclic compound be converted to a heterocycle?
After all, every carbocyclic compound, regardless of structure and functionality, may in principle be converted into a collection of heterocyclic analogs by replacing one or more of the ring carbon atoms with a different element.
What are some examples of heterocyclic natural products?
By clicking on the above diagram some other examples of heterocyclic natural products will be displayed. Oxiranes (epoxides) are the most commonly encountered three-membered heterocycles. Epoxides are easily prepared by reaction of alkenes with peracids, usually with good stereospecificity.
What are heterocyclic amines (HCAs)?
S.-W. Choi, J.B. Mason, in Encyclopedia of Food Sciences and Nutrition (Second Edition), 2003 Heterocyclic amines (HCAs) are the carcinogenic and mutagenic chemicals formed from cooking muscle meats such as beef, pork, fowl, and fish.
