What is a palatal tremor?
What is a palatal tremor?
A tremor is an involuntary, rhythmic and oscillatory movement of one or more body parts at a fixed amplitude and frequency [ 1, 2, 3 ]. A palatal tremor (PT) is a rare type of tremor involving the soft palate. It can be unilateral or bilateral [ 1, 2 ].
Is progressive ataxia and palatal tremor (PAPT) heterogeneous?
Palatal tremor has been subdivided into essential (EPT) and symptomatic palatal tremor (SPT). A subgroup of the SPT form has a syndrome of progressive ataxia and palatal tremor (PAPT). Published details of cases of PAPT are sparse and the disorder appears heterogeneous. We present clinical and MRI f …
Can the cycle of palatal tremor be reset by stimulation of trigeminal afferents?
The cycle of palatal tremor could not be reset by stimulation of trigeminal afferents in either EPT or SPT patients, and Valsalva’s manoeuvre did not consistently affect the rhythm of the tremor in either group.
Is the EPT central to the origin of the tremors?
Another observation to support the central origin of the EPT is the response of said tremors to centrally-acting drugs like lamotrigine, sodium valproate and falunarizine [ 12, 13, 14 ]. However, these were presented through anecdotal evidence and no placebo-controlled trial was ever conducted to assess the true response.